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Maintenance Treatment for Psoriasis

Maintenance Treatment for Psoriasis Abstract To the Editor.— Psoralens plus long-wave ultraviolet radiation (PUVA) treatment for psoriasis is now widely used, possibly more in some European countries than in the United States. It is generally said that after an initial series of 20 to 30 irradiations, 95% or more clearing is obtained in 90% of patients. Most investigators then use a maintenance schedule consisting of one treatment every week or less, while others abstain from further irradiation.Treatment with PUVA was started in our institution in 100 patients with extensive psoriasis in the last quarter of 1976 and in 1977; two patients dropped out of the study for personal reasons and one failed to return after one irradiation because of "burning." The results can now be evaluated after an interval of one year or more.Of the 97 patients who completed the initial treatment, more than 95% clearing was obtained in 65 patients, 75% to References 1. Farber EM, Abel EA, Schaefer H: PUVA appraisal . Br J Dermatol 99:715-717, 1978.Crossref 2. Epstein JH: Risks and benefits of the treatment of psoriasis . N Engl J Med 300:852-853, 1979.Crossref 3. Melski JW, Tenenbaum L, Parrish JA, et al: Oral methoxsalen photochemotherapy for the treatment of psoriasis: A cooperative clinical trial . J Invest Dermatol 68:328-335, 1977.Crossref 4. Lynch WS, Roenigk HH Jr: Essentials of PUVA therapy . Cutis 20:494-501, 1977. 5. Morison WL, Parrish JA, Fitzpatrick TB: Controlled study of PUVA and adjunctive topical therapy in the management of psoriasis . Br J Dermatol 98:125-132, 1978.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Maintenance Treatment for Psoriasis

De Bersaques, J.
Archives of Dermatology , Volume 115 (9) – Sep 1, 1979
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Maintenance Treatment for Psoriasis

Abstract

Abstract To the Editor.— Psoralens plus long-wave ultraviolet radiation (PUVA) treatment for psoriasis is now widely used, possibly more in some European countries than in the United States. It is generally said that after an initial series of 20 to 30 irradiations, 95% or more clearing is obtained in 90% of patients. Most investigators then use a maintenance schedule consisting of one treatment every week or less, while others abstain from further irradiation.Treatment with PUVA was...
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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1979.04010090001001
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— Psoralens plus long-wave ultraviolet radiation (PUVA) treatment for psoriasis is now widely used, possibly more in some European countries than in the United States. It is generally said that after an initial series of 20 to 30 irradiations, 95% or more clearing is obtained in 90% of patients. Most investigators then use a maintenance schedule consisting of one treatment every week or less, while others abstain from further irradiation.Treatment with PUVA was started in our institution in 100 patients with extensive psoriasis in the last quarter of 1976 and in 1977; two patients dropped out of the study for personal reasons and one failed to return after one irradiation because of "burning." The results can now be evaluated after an interval of one year or more.Of the 97 patients who completed the initial treatment, more than 95% clearing was obtained in 65 patients, 75% to References 1. Farber EM, Abel EA, Schaefer H: PUVA appraisal . Br J Dermatol 99:715-717, 1978.Crossref 2. Epstein JH: Risks and benefits of the treatment of psoriasis . N Engl J Med 300:852-853, 1979.Crossref 3. Melski JW, Tenenbaum L, Parrish JA, et al: Oral methoxsalen photochemotherapy for the treatment of psoriasis: A cooperative clinical trial . J Invest Dermatol 68:328-335, 1977.Crossref 4. Lynch WS, Roenigk HH Jr: Essentials of PUVA therapy . Cutis 20:494-501, 1977. 5. Morison WL, Parrish JA, Fitzpatrick TB: Controlled study of PUVA and adjunctive topical therapy in the management of psoriasis . Br J Dermatol 98:125-132, 1978.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Sep 1, 1979

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