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Basal Cell Layer Antibodies in Patients With Burns-Reply

Basal Cell Layer Antibodies in Patients With Burns-Reply This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— The data presented by Drs Ablin and Holder confirm that BCL antibodies occur in patients with burns. Other investigators have shown that there is also a high incidence of intercellular and basement membrane zone antibodies in these patients. These observations suggest that the type of injury to skin caused by burns leads to the formation of antibodies to a wide variety of epidermal antigens. Whether the antibodies in turn play a role in prolonging or aggravating tissue injury is presently unknown.The true incidence of BCL antibodies in patients with burns is presently unclear. A wide variation in incidences has been reported in the few studies that have been performed, as shown in Dr Ablin's table. This variation is to be expected from the different substrates and serum dilutions used in the assays. Basal cell layer antibodies are usually more reactive to some substrates (guinea pig esophagus, for http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Basal Cell Layer Antibodies in Patients With Burns-Reply

Bystryn, Jean-Claude
Archives of Dermatology , Volume 115 (8) – Aug 1, 1979
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Basal Cell Layer Antibodies in Patients With Burns-Reply

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— The data presented by Drs Ablin and Holder confirm that BCL antibodies occur in patients with burns. Other investigators have shown that there is also a high incidence of intercellular and basement membrane zone antibodies in these patients. These observations suggest that the type of injury to skin caused by burns leads to the...
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Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1979.04010080004009
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In Reply.— The data presented by Drs Ablin and Holder confirm that BCL antibodies occur in patients with burns. Other investigators have shown that there is also a high incidence of intercellular and basement membrane zone antibodies in these patients. These observations suggest that the type of injury to skin caused by burns leads to the formation of antibodies to a wide variety of epidermal antigens. Whether the antibodies in turn play a role in prolonging or aggravating tissue injury is presently unknown.The true incidence of BCL antibodies in patients with burns is presently unclear. A wide variation in incidences has been reported in the few studies that have been performed, as shown in Dr Ablin's table. This variation is to be expected from the different substrates and serum dilutions used in the assays. Basal cell layer antibodies are usually more reactive to some substrates (guinea pig esophagus, for

Journal

Archives of Dermatology – American Medical Association

Published: Aug 1, 1979

There are no references for this article.