Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Generalized Connective Tissue Nevi and Ichthyosis in Down's Syndrome

Generalized Connective Tissue Nevi and Ichthyosis in Down's Syndrome Abstract The first description of a localized connective tissue nevus with a decreased amount of elastic tissue is credited to Lewandowsky in 1921. Various authors designated these localized hamartomas as nevus anelasticus according to the histologic presentation of the nevus. Sachs1 reported a generalized process that developed after furunculosis and Loewenthal2 described a case in which the lesions became generalized over a ten-year period. We report a case of generalized connective tissue nevi with a decrease in elastic tissue in a patient with Down's syndrome. Report of a Case A 47-year-old man who had Down's syndrome was admitted to Bronx Municipal Medical Center, New York, for treatment of sepsis. His family related a history of crops of boils that appeared approximately ten years ago. After draining a whitish material, there were residual nodules. Simultaneously, a "mossy appearance" of the skin occurred at the periphery of the nodules. There was no References 1. Sachs 0: Zur frage der circumscripten bindegewebigen hautveranderungen . Arch Dermatol Syphilol 152:273-282, 1926. 2. Loewenthal LJA: Connective tissue naevi and collangénome eruptif. Dermatologica 114:81-90, 1957.Crossref 3. Rague CJ, Wood MG: Connective-tissue nevus: Dermatofibrosis lenticularis disseminata with osteopoikilosis . Arch Dermatol 102:390-396, 1970.Crossref 4. Lever WF, Schaumburg-Lever G: Histopathology of the Skin , ed 5. Philadelphia, JB Lippincott Co, 1975, pp 79-80. 5. Musso LA: Some observations on elastic tissue formation . Australas J Dermatol 17:22-25, 1976.Crossref 6. Esterly NB: The ichthyosiform dermatoses . Pediatrics 92:990-1004, 1968. 7. Carter DM, Jegasothy BV: Alopecia areata and Down syndrome . Arch Dermatol 112:1397-1399, 1976.Crossref 8. Kersting DW, Rapaport I: A clinicopathologic study of the skin in mongolism . Arch Dermatol 77:319-323, 1958.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Generalized Connective Tissue Nevi and Ichthyosis in Down's Syndrome

Archives of Dermatology , Volume 115 (5) – May 1, 1979

Loading next page...
 
/lp/american-medical-association/generalized-connective-tissue-nevi-and-ichthyosis-in-down-s-syndrome-pEIla1H9k2

References (9)

Publisher
American Medical Association
Copyright
Copyright © 1979 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1979.04010050053019
Publisher site
See Article on Publisher Site

Abstract

Abstract The first description of a localized connective tissue nevus with a decreased amount of elastic tissue is credited to Lewandowsky in 1921. Various authors designated these localized hamartomas as nevus anelasticus according to the histologic presentation of the nevus. Sachs1 reported a generalized process that developed after furunculosis and Loewenthal2 described a case in which the lesions became generalized over a ten-year period. We report a case of generalized connective tissue nevi with a decrease in elastic tissue in a patient with Down's syndrome. Report of a Case A 47-year-old man who had Down's syndrome was admitted to Bronx Municipal Medical Center, New York, for treatment of sepsis. His family related a history of crops of boils that appeared approximately ten years ago. After draining a whitish material, there were residual nodules. Simultaneously, a "mossy appearance" of the skin occurred at the periphery of the nodules. There was no References 1. Sachs 0: Zur frage der circumscripten bindegewebigen hautveranderungen . Arch Dermatol Syphilol 152:273-282, 1926. 2. Loewenthal LJA: Connective tissue naevi and collangénome eruptif. Dermatologica 114:81-90, 1957.Crossref 3. Rague CJ, Wood MG: Connective-tissue nevus: Dermatofibrosis lenticularis disseminata with osteopoikilosis . Arch Dermatol 102:390-396, 1970.Crossref 4. Lever WF, Schaumburg-Lever G: Histopathology of the Skin , ed 5. Philadelphia, JB Lippincott Co, 1975, pp 79-80. 5. Musso LA: Some observations on elastic tissue formation . Australas J Dermatol 17:22-25, 1976.Crossref 6. Esterly NB: The ichthyosiform dermatoses . Pediatrics 92:990-1004, 1968. 7. Carter DM, Jegasothy BV: Alopecia areata and Down syndrome . Arch Dermatol 112:1397-1399, 1976.Crossref 8. Kersting DW, Rapaport I: A clinicopathologic study of the skin in mongolism . Arch Dermatol 77:319-323, 1958.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: May 1, 1979

There are no references for this article.