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Clindamycin Therapy for Moderately Severe Acne

Clindamycin Therapy for Moderately Severe Acne This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— As a specialist in infectious diseases, I believe that a few words of comment are in order with regard to the article by Christian and Krueger that appeared recently in the Archives. I must say that I think the authors have underestimated the potential gravity of the toxicity that has been associated with clindamycin, and I feel that their conclusion "that clindamycin is probably a valuable additional drug in the treatment of acne" was somewhat incautious. Clindamycin is undoubtedly a very effective drug for a number of conditions. Sufficient verification of its toxicity, particularly with regard to the gastrointestinal tract, now exists, however, to make a thoughtful physician pause before using it for a disease that does not seriously threaten the general health of his patient. This is particularly true when alternative forms of therapy of known efficacy and a low order of toxicity are available, and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Clindamycin Therapy for Moderately Severe Acne

Finley, Richard A.
Archives of Dermatology , Volume 112 (9) – Sep 1, 1976
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Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1976.01630330077027
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— As a specialist in infectious diseases, I believe that a few words of comment are in order with regard to the article by Christian and Krueger that appeared recently in the Archives. I must say that I think the authors have underestimated the potential gravity of the toxicity that has been associated with clindamycin, and I feel that their conclusion "that clindamycin is probably a valuable additional drug in the treatment of acne" was somewhat incautious. Clindamycin is undoubtedly a very effective drug for a number of conditions. Sufficient verification of its toxicity, particularly with regard to the gastrointestinal tract, now exists, however, to make a thoughtful physician pause before using it for a disease that does not seriously threaten the general health of his patient. This is particularly true when alternative forms of therapy of known efficacy and a low order of toxicity are available, and

Journal

Archives of Dermatology – American Medical Association

Published: Sep 1, 1976

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