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NEW ENGLAND DERMATOLOGICAL SOCIETY

NEW ENGLAND DERMATOLOGICAL SOCIETY Abstract Pityriasis Rubra Pilaris: An Unusual Case. Presented by Irwin Braverman, MD. A 37-year-old white woman developed a pruritic erythematous lesion on her right breast 17 years ago that slowly spread to involve most of her body, but spared the palms and soles. Scalp lesions appeared ten years ago as crusting, pruritic areas that evolved into scarring alopecia. She has been treated with electron beam therapy, prednisone, vitamin A, methotrexate, and flurandrenolide cream. Family history was noncontributory.Examination revealed scarring alopecia over the central portion of the scalp. Perifollicular, hyperkeratotic lesions were present over the entire surface of her body, particularly the extensor surfaces of the extremities, the belt line, the upper anterior chest, and the buttocks. Small hyperkeratotic plaques with "carpet tacking" and surrounding erythema were localized to the nose and malar areas.Laboratory data were normal except for eosinophilia. D-xylose and vitamin A absorption tests were normal.Pathologic findings References 1. Anderson TE, Spackman TJ, Schwartz SS: Roentgen findings in intestinal ganglioneuromatosis: Its association with medullary thyroid carcinoma and pheochromocytoma . Radiology 101:93-96, 1971.Crossref 2. Eisenberg AA, Wallerstein H: Pheochromocytoma of the suprarenal medulla (paraganglioneuroma): A clinicopathological study . Arch Pathol 14:818-836, 1932. 3. Sipple JH: Association of pheochromocytoma with carcinoma of the thyroid gland . Am J Med 31:163-166, 1961.Crossref 4. Baum JL, Adler ME: Pheochromocytoma, medullary thyroid carcinoma, multiple mucosal neuroma: A variant of the syndrome . Arch Ophthalmol 87:574-584, 1972.Crossref 5. Jackson CE, Tashjian AH Jr, Block MA: Detection of medullary thyroid cancer by calcitonin assay in families . Ann Intern Med 78:845-852, 1973.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

NEW ENGLAND DERMATOLOGICAL SOCIETY

Archives of Dermatology , Volume 110 (1) – Jul 1, 1974

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1974.01630070092040
Publisher site
See Article on Publisher Site

Abstract

Abstract Pityriasis Rubra Pilaris: An Unusual Case. Presented by Irwin Braverman, MD. A 37-year-old white woman developed a pruritic erythematous lesion on her right breast 17 years ago that slowly spread to involve most of her body, but spared the palms and soles. Scalp lesions appeared ten years ago as crusting, pruritic areas that evolved into scarring alopecia. She has been treated with electron beam therapy, prednisone, vitamin A, methotrexate, and flurandrenolide cream. Family history was noncontributory.Examination revealed scarring alopecia over the central portion of the scalp. Perifollicular, hyperkeratotic lesions were present over the entire surface of her body, particularly the extensor surfaces of the extremities, the belt line, the upper anterior chest, and the buttocks. Small hyperkeratotic plaques with "carpet tacking" and surrounding erythema were localized to the nose and malar areas.Laboratory data were normal except for eosinophilia. D-xylose and vitamin A absorption tests were normal.Pathologic findings References 1. Anderson TE, Spackman TJ, Schwartz SS: Roentgen findings in intestinal ganglioneuromatosis: Its association with medullary thyroid carcinoma and pheochromocytoma . Radiology 101:93-96, 1971.Crossref 2. Eisenberg AA, Wallerstein H: Pheochromocytoma of the suprarenal medulla (paraganglioneuroma): A clinicopathological study . Arch Pathol 14:818-836, 1932. 3. Sipple JH: Association of pheochromocytoma with carcinoma of the thyroid gland . Am J Med 31:163-166, 1961.Crossref 4. Baum JL, Adler ME: Pheochromocytoma, medullary thyroid carcinoma, multiple mucosal neuroma: A variant of the syndrome . Arch Ophthalmol 87:574-584, 1972.Crossref 5. Jackson CE, Tashjian AH Jr, Block MA: Detection of medullary thyroid cancer by calcitonin assay in families . Ann Intern Med 78:845-852, 1973.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Jul 1, 1974

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