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Acanthosis Nigricans Following Diethylstilbestrol Therapy: Occurrence in Patients With Childhood Muscular Dystrophy

Acanthosis Nigricans Following Diethylstilbestrol Therapy: Occurrence in Patients With Childhood... Abstract Acanthosis nigricans developed in two brothers with childhood (Duchenne) muscular dystrophy who were among six patients receiving diethylstilbestrol as an experimental treatment of their muscle disease. These observations and others suggest that estrogen may play some role in the development of this relatively uncommon skin disorder. References 1. Cohen L, et al: Serum enzyme lowering and other effects of diethylstilbestrol in Duchenne's muscular dystrophy . J Lab Clin Med 78:797-798, 1971. 2. Cohen L, Morgan J, Schulman S: Diethylstilbestrol: Observation on its use in Duchenne's muscular dystrophy . Proc Soc Exp Biol Med 140:830-835, 1972.Crossref 3. Vignos PJ, Archibald KC: Maintenance of ambulation in childhood muscular dystrophy . J Chronic Dis 12:273-290, 1960.Crossref 4. Cobenour W, Gamble JW: Acanthosis nigricans: Review of literature and report of cases . J Oral Surg 29:48-51, 1971. 5. Pollitzer S: Acanthosis nigricans , in Unna PG, et al (eds): International Atlas of Rare Skin Diseases . London, HK Lewis & Co Ltd, 1890, part (4) , p 4. 6. Janovsky V: Acanthosis nigricans , in Unna PG, et al (eds): International Atlas of Rare Skin Diseases . London, HK Lewis & Co Ltd, 1890, part (4) , p 1. 7. Brown J, Winkelmann PK: Acanthosis nigricans: A study of 90 cases . Medicine 47:33-51, 1968.Crossref 8. Acanthosis nigricans following prolonged use of stilbestrol, SOCIETY TRANSACTIONS . Arch Dermatol 81:153-154, 1960. 9. Katzenellenbogan T: Dermatoendocrinological syndrome due to diethylstilbestrol . JAMA 161:1695-1696, 1956.Crossref 10. Curth HO, Stanetz CA: Acanthosis nigricans and cancer of the liver of a dog . Am J Cancer 37:216-223, 1939. 11. Raynolds SPM, Foster FI: Peripheral vascular action of estrogens in the human male . J Clin Invest 18:649-655, 1939.Crossref 12. Schiff M, Burn HF: The effect of intravenous estrogens on ground substance . Arch Otolaryngol 73:63-71, 1961.Crossref 13. David ME, et al: Studies on pigmentation of endocrine origin . J Clin Endocrinol Metab 5:138-145, 1945.Crossref 14. Rothman S: Pituitary basophilism in the juvenile type of acanthosis nigricans . JAMA 156:242-244, 1954.Crossref 15. Lerner AB: On the cause of acanthosis nigricans . N Eng J Med 281:706-707, 1969.Crossref 16. Merimee TJ, Burgess JA, Rabinowitz D: Sex-determined variation in serum insulin and growth hormone response to amino acid stimulation . J Clin Endocrinol Metab 26:791-793, 1966.Crossref 17. Frantz AG, Rabkin MT: Effects of estrogen and sex difference on secretion of human growth hormone . J Clin Endocrinol Metab 25:1470-1480, 1965.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Acanthosis Nigricans Following Diethylstilbestrol Therapy: Occurrence in Patients With Childhood Muscular Dystrophy

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References (17)

Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1974.01630040051013
Publisher site
See Article on Publisher Site

Abstract

Abstract Acanthosis nigricans developed in two brothers with childhood (Duchenne) muscular dystrophy who were among six patients receiving diethylstilbestrol as an experimental treatment of their muscle disease. These observations and others suggest that estrogen may play some role in the development of this relatively uncommon skin disorder. References 1. Cohen L, et al: Serum enzyme lowering and other effects of diethylstilbestrol in Duchenne's muscular dystrophy . J Lab Clin Med 78:797-798, 1971. 2. Cohen L, Morgan J, Schulman S: Diethylstilbestrol: Observation on its use in Duchenne's muscular dystrophy . Proc Soc Exp Biol Med 140:830-835, 1972.Crossref 3. Vignos PJ, Archibald KC: Maintenance of ambulation in childhood muscular dystrophy . J Chronic Dis 12:273-290, 1960.Crossref 4. Cobenour W, Gamble JW: Acanthosis nigricans: Review of literature and report of cases . J Oral Surg 29:48-51, 1971. 5. Pollitzer S: Acanthosis nigricans , in Unna PG, et al (eds): International Atlas of Rare Skin Diseases . London, HK Lewis & Co Ltd, 1890, part (4) , p 4. 6. Janovsky V: Acanthosis nigricans , in Unna PG, et al (eds): International Atlas of Rare Skin Diseases . London, HK Lewis & Co Ltd, 1890, part (4) , p 1. 7. Brown J, Winkelmann PK: Acanthosis nigricans: A study of 90 cases . Medicine 47:33-51, 1968.Crossref 8. Acanthosis nigricans following prolonged use of stilbestrol, SOCIETY TRANSACTIONS . Arch Dermatol 81:153-154, 1960. 9. Katzenellenbogan T: Dermatoendocrinological syndrome due to diethylstilbestrol . JAMA 161:1695-1696, 1956.Crossref 10. Curth HO, Stanetz CA: Acanthosis nigricans and cancer of the liver of a dog . Am J Cancer 37:216-223, 1939. 11. Raynolds SPM, Foster FI: Peripheral vascular action of estrogens in the human male . J Clin Invest 18:649-655, 1939.Crossref 12. Schiff M, Burn HF: The effect of intravenous estrogens on ground substance . Arch Otolaryngol 73:63-71, 1961.Crossref 13. David ME, et al: Studies on pigmentation of endocrine origin . J Clin Endocrinol Metab 5:138-145, 1945.Crossref 14. Rothman S: Pituitary basophilism in the juvenile type of acanthosis nigricans . JAMA 156:242-244, 1954.Crossref 15. Lerner AB: On the cause of acanthosis nigricans . N Eng J Med 281:706-707, 1969.Crossref 16. Merimee TJ, Burgess JA, Rabinowitz D: Sex-determined variation in serum insulin and growth hormone response to amino acid stimulation . J Clin Endocrinol Metab 26:791-793, 1966.Crossref 17. Frantz AG, Rabkin MT: Effects of estrogen and sex difference on secretion of human growth hormone . J Clin Endocrinol Metab 25:1470-1480, 1965.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Apr 1, 1974

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