Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Malignant Lymphoma, Reticulum Cell Type: Ultrastructural and Cytological Demonstration of Lutzner Cells

Malignant Lymphoma, Reticulum Cell Type: Ultrastructural and Cytological Demonstration of Lutzner... Abstract Reticulum cell sarcoma in a patient presented an initial picture of mycosis fungoides d'emblee. Atypical cells with indented convoluted nuclei similar to those described by Lutzner were demonstrated electron microscopically in skin tumors. On light microscopy, 1μ epoxy-embedded specimens from the lymph node and several internal organs involved by the process revealed similar cells with these indented nuclei. It is felt that the "Lutzner cell" is not a specific indicator of mycosis fungoides, but may be found in other types of lymphomas. Whether it can occur in completely different dermatoses or is a characteristic cell that is distinctive for the lymphomas as a group requires further investigation. References 1. Bluefarb SM: Cutaneous Manifestations of the Malignant Lymphomas . Springfield, Ill, Charles C Thomas Publisher, 1959, pp 109-120. 2. Lapiere S: The realm and frontiers of mycosis fungoides . J Invest Derm 42:101-103, 1964. 3. Lutzner MA, Jordon H: Ultrastructural features of a bizarre nucleus found in the Sezary cell and characteristics of an abnormal cell from mycosis fungoides , abstracted. Clin Res 15:252, 1967. 4. Lutzner MA: The ultrastructure of an abnormal cell in Sezary's syndrome . Blood 31:719-726, 1968. 5. Brownlee TR, Murad TM: Ultrastructure of mycosis fungoides . Cancer 26:686-698, 1970.Crossref 6. Maguire A: Treatment of mycosis fungoides with cyclophosphamide and chlorpromazine . Brit J Derm 80:54-57, 1968.Crossref 7. Vidal E, Brocq L: Eturde sur le mycosis fungoide . France Med 2:946, 1885. 8. Alibert JLM: Monographie des Dermatoses , ed 2. Paris, G Bailliere, 1835, p 413. 9. Clendenning WE, Brecher G, Van Scott EJ: Mycosis fungoides: Relationship to malignant cutaneous reticulosis and the Sezary syndrome . Arch Derm 89:785-792, 1964.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Malignant Lymphoma, Reticulum Cell Type: Ultrastructural and Cytological Demonstration of Lutzner Cells

Download PDF
7 pages

Loading next page...
 
/lp/american-medical-association/malignant-lymphoma-reticulum-cell-type-ultrastructural-and-cytological-jFhFMFozNA

References (9)

Publisher
American Medical Association
Copyright
Copyright © 1971 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1971.04000190040006
Publisher site
See Article on Publisher Site

Abstract

Abstract Reticulum cell sarcoma in a patient presented an initial picture of mycosis fungoides d'emblee. Atypical cells with indented convoluted nuclei similar to those described by Lutzner were demonstrated electron microscopically in skin tumors. On light microscopy, 1μ epoxy-embedded specimens from the lymph node and several internal organs involved by the process revealed similar cells with these indented nuclei. It is felt that the "Lutzner cell" is not a specific indicator of mycosis fungoides, but may be found in other types of lymphomas. Whether it can occur in completely different dermatoses or is a characteristic cell that is distinctive for the lymphomas as a group requires further investigation. References 1. Bluefarb SM: Cutaneous Manifestations of the Malignant Lymphomas . Springfield, Ill, Charles C Thomas Publisher, 1959, pp 109-120. 2. Lapiere S: The realm and frontiers of mycosis fungoides . J Invest Derm 42:101-103, 1964. 3. Lutzner MA, Jordon H: Ultrastructural features of a bizarre nucleus found in the Sezary cell and characteristics of an abnormal cell from mycosis fungoides , abstracted. Clin Res 15:252, 1967. 4. Lutzner MA: The ultrastructure of an abnormal cell in Sezary's syndrome . Blood 31:719-726, 1968. 5. Brownlee TR, Murad TM: Ultrastructure of mycosis fungoides . Cancer 26:686-698, 1970.Crossref 6. Maguire A: Treatment of mycosis fungoides with cyclophosphamide and chlorpromazine . Brit J Derm 80:54-57, 1968.Crossref 7. Vidal E, Brocq L: Eturde sur le mycosis fungoide . France Med 2:946, 1885. 8. Alibert JLM: Monographie des Dermatoses , ed 2. Paris, G Bailliere, 1835, p 413. 9. Clendenning WE, Brecher G, Van Scott EJ: Mycosis fungoides: Relationship to malignant cutaneous reticulosis and the Sezary syndrome . Arch Derm 89:785-792, 1964.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Jul 1, 1971

There are no references for this article.