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S. Rothman, J. Rubin (1942)
Sunburn and Para-Aminobenzoic Acid1Journal of Investigative Dermatology, 5
G. Kahn, G. Wilcox (1969)
Sunscreen testing using sunlight: photographic and in vivo methods compared.The Journal of investigative dermatology, 53 3
M. Pathak, T. Fitzpatrick, E. Frenk (1969)
Evaluation of topical agents that prevent sunburn--superiority of para-aminobenzoic acid and its ester in ethyl alcohol.The New England journal of medicine, 280 26
Abstract Four topical sunscreening preparations were tested in midday clear bright Florida sunshine. Five percent para-aminobenzoic acid (PABA) in 70% ethanol and a cream containing benzophenone derivatives oxybenzone and dioxybenzone (Solbar) were found to be good sunscreens. A new formulation using an ester of a modified PABA (Blockout) was less protective. All of the agents washed off when the subjects swam for ten minutes. Three of nine subjects complained of a burning sensation and developed an immediate bright erythema 30 minutes after application of Blockout and exposure to the sun. References 1. Pathak MA, Fitzpatrick TB, Frenk E: Evaluation of topical agents that prevent sunburn: Superiority of para-aminobenzoic acid and its ester in ethyl alcohol . New Eng J Med 280:1459, 1969.Crossref 2. Rothman S, Rubin J: Sunburn and para-aminobenzoic acid . J Invest Derm 5:445, 1942.Crossref 3. Kahn G, Wilcox G: Sunscreen testing using sunlight: Photographic and in vivo methods compared J Invest Derm 53:200, 1969.Crossref
Archives of Dermatology – American Medical Association
Published: Apr 1, 1970
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