Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Photocontact Allergic Reactions: Elicitation by Low Doses of Long Ultraviolet Rays

Photocontact Allergic Reactions: Elicitation by Low Doses of Long Ultraviolet Rays Abstract Subjects experimentally photocontact sensitized to tetrachlorosalicylanilide (TCSA), tribromosalicylanilide (TBS), and bithionol were studied with regard to the quantity of long ultraviolet rays (UV) necessary to elicit reactions. Less than one second of high energy long UV, about 20 seconds or less of midday summer sunlight, will elicit photoallergic reactions in highly sensitized persons. Unlike sunburn, photoallergic reactions can readily occur on the hairy scalp and palms, though usually of lesser intensity. Reactions can be elicited through cotton and woolen cloth, adhesive tape, and bond paper. Two thicknesses of desk blotter paper afford a complete light seal. References 1. Freeman, R.G., and Knox, J.M.: The Action Spectrum of Photocontact Dermatitis , Arch Derm 97:130-136 ( (Feb) ) 1968.Crossref 2. Cripps, D.J., and Enta, T.: The Action Spectra of Tribromosalicylanilide Photosensitivity , abstracted, Clin Res 15:248 ( (April) ) 1967. 3. Harber, L.C.; Harris, H.; and Baer, R.L.: Photoallergic Contact Dermatitis , Arch Derm 94:255-262 ( (Sept) ) 1966.Crossref 4. Epstein, J.H.; Wuepper, K.D.; and Maibach, H.I.: Photocontact Dermatitis to Halogenated Salicylanilides and Related Compounds , Arch Derm 97:236-244 ( (March) ) 1968Crossref 5. Osmundsen, P.E.: Contact Photodermatitis Due to Tribromosalicylanilide , Brit J Derm 80:228-234 ( (April) ) 1968.Crossref 6. Epstein, S.: "Masked" Photopatch Tests , J Invest Derm 41:369-370 ( (Dec) ) 1963.Crossref 7. Urbach, F.: Solar Simulation for Phototesting of Human Skin , read before the 1966 Rutgers Conference on Biologic Effects of Ultraviolet Radiation. 8. Kligman, A.M.: The Identification of Contact Allergens by Human Assay: The Maximization Test , J Invest Derm 47:393-409 ( (Nov) ) 1966.Crossref 9. Johnson, B.E.; Daniels, F., Jr.; and Magnus, I.A.: " Response of Human Skin to Ultraviolet Light ," in Photophysiology , New York: Academic Press, Inc., 1968, vol 4, pp 139-202. 10. Christensen, B.C., and Buchmann, B.: " The Normal Sensitivity of Human Skin to 250-300 nn Ultraviolet Irradiation and its Dependence on the Thickness of the Stratum Corneum ," in Progress in Photobiology: Proceedings of the Third International Congress on Photobiology , Amsterdam, p 331-332. 11. Tregear, R.: Physical Functions of Skin , New York: Academic Press, Inc., 1966. 12. Willis, I., and Kligman, A.M.: The Mechanism of Photoallergic Contact Dermatitis , J Invest Derm 51:378-384 ( (Nov) ) 1968.Crossref 13. Buck, H.W.; Magnus, I.A.; and Porter, A.D.: The Action Spectrum of 8-Methoxypsoralen for Erythema in Human Skin , Brit J Derm 72:249-255 ( (July) ) 1960.Crossref 14. O'Quinn, S.E.; Kennedy, C.B.; and Isabell, K.H.: Contact Photodermatitis Due to Bithionol and Related Compounds , JAMA 199:125-128 ( (Jan 9) ) 1967.Crossref 15. Fulton, J.E., and Willis, I.: Photoallergy to Methoxsalen , Arch Derm 98:445-450 ( (Nov) ) 1968.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Photocontact Allergic Reactions: Elicitation by Low Doses of Long Ultraviolet Rays

Archives of Dermatology , Volume 100 (5) – Nov 1, 1969

Loading next page...
 
/lp/american-medical-association/photocontact-allergic-reactions-elicitation-by-low-doses-of-long-7ty1vkIddk

References (16)

Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1969.01610290019004
Publisher site
See Article on Publisher Site

Abstract

Abstract Subjects experimentally photocontact sensitized to tetrachlorosalicylanilide (TCSA), tribromosalicylanilide (TBS), and bithionol were studied with regard to the quantity of long ultraviolet rays (UV) necessary to elicit reactions. Less than one second of high energy long UV, about 20 seconds or less of midday summer sunlight, will elicit photoallergic reactions in highly sensitized persons. Unlike sunburn, photoallergic reactions can readily occur on the hairy scalp and palms, though usually of lesser intensity. Reactions can be elicited through cotton and woolen cloth, adhesive tape, and bond paper. Two thicknesses of desk blotter paper afford a complete light seal. References 1. Freeman, R.G., and Knox, J.M.: The Action Spectrum of Photocontact Dermatitis , Arch Derm 97:130-136 ( (Feb) ) 1968.Crossref 2. Cripps, D.J., and Enta, T.: The Action Spectra of Tribromosalicylanilide Photosensitivity , abstracted, Clin Res 15:248 ( (April) ) 1967. 3. Harber, L.C.; Harris, H.; and Baer, R.L.: Photoallergic Contact Dermatitis , Arch Derm 94:255-262 ( (Sept) ) 1966.Crossref 4. Epstein, J.H.; Wuepper, K.D.; and Maibach, H.I.: Photocontact Dermatitis to Halogenated Salicylanilides and Related Compounds , Arch Derm 97:236-244 ( (March) ) 1968Crossref 5. Osmundsen, P.E.: Contact Photodermatitis Due to Tribromosalicylanilide , Brit J Derm 80:228-234 ( (April) ) 1968.Crossref 6. Epstein, S.: "Masked" Photopatch Tests , J Invest Derm 41:369-370 ( (Dec) ) 1963.Crossref 7. Urbach, F.: Solar Simulation for Phototesting of Human Skin , read before the 1966 Rutgers Conference on Biologic Effects of Ultraviolet Radiation. 8. Kligman, A.M.: The Identification of Contact Allergens by Human Assay: The Maximization Test , J Invest Derm 47:393-409 ( (Nov) ) 1966.Crossref 9. Johnson, B.E.; Daniels, F., Jr.; and Magnus, I.A.: " Response of Human Skin to Ultraviolet Light ," in Photophysiology , New York: Academic Press, Inc., 1968, vol 4, pp 139-202. 10. Christensen, B.C., and Buchmann, B.: " The Normal Sensitivity of Human Skin to 250-300 nn Ultraviolet Irradiation and its Dependence on the Thickness of the Stratum Corneum ," in Progress in Photobiology: Proceedings of the Third International Congress on Photobiology , Amsterdam, p 331-332. 11. Tregear, R.: Physical Functions of Skin , New York: Academic Press, Inc., 1966. 12. Willis, I., and Kligman, A.M.: The Mechanism of Photoallergic Contact Dermatitis , J Invest Derm 51:378-384 ( (Nov) ) 1968.Crossref 13. Buck, H.W.; Magnus, I.A.; and Porter, A.D.: The Action Spectrum of 8-Methoxypsoralen for Erythema in Human Skin , Brit J Derm 72:249-255 ( (July) ) 1960.Crossref 14. O'Quinn, S.E.; Kennedy, C.B.; and Isabell, K.H.: Contact Photodermatitis Due to Bithionol and Related Compounds , JAMA 199:125-128 ( (Jan 9) ) 1967.Crossref 15. Fulton, J.E., and Willis, I.: Photoallergy to Methoxsalen , Arch Derm 98:445-450 ( (Nov) ) 1968.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Nov 1, 1969

There are no references for this article.