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Contact Photosensitivity Dermatitis From Sun-protective Agent

Contact Photosensitivity Dermatitis From Sun-protective Agent Abstract A popular commercial sunscreening agent containing the ultraviolet-absorbing chemical glyceryl p-aminobenzoate was found to be a photosensitizer having produced a severe dermatitis in a patient who applied it prior to sun exposure. Three possible mechanisms of action are briefly discussed: photoallergy, phototoxicity, and photoaugmentation. The agent was shown to be an ordinary contact allergen as well as a photosensitizer. References 1. Wuepper, K.D.: Paraben Contact Dermatitis , JAMA 202:579-581 ( (Nov) ) 1967.Crossref 2. Epstein, S.: Simplified Photopatch Testing , Arch Derm 93:216-220 ( (Feb) ) 1966.Crossref 3. Epstein, S.: The Photopatch Test, Its Technique, Manifestation, and Significance , Ann Allerg 22:1-11 ( (Jan) ) 1964. 4. Shelley, W.B.: The Patch Test , JAMA 200:874-878 ( (June 5) ) 1967.Crossref 5. Fisher, A.A.: Contact Dermatitis , Philadelphia: Lea & Febiger, Publisher, 1967. 6. Baer, R.L., and Harber L.C.: Photosensitivity Induced by Drugs , JAMA 192:989-990 ( (June 14) ) 1965.Crossref 7. Jillson, O.F., and Baughman, R.D.: Contact Photodermatitis From Bithionol , Arch Derm 88:409-418 ( (Oct) ) 1963.Crossref 8. O'Quinn, S.E.; Kennedv, C.B.; and Isbell, K.H.: Contact Photodermatitis Due to Bithionol and Related Compounds . JAMA 199:89-92 ( (Jan 9) ) 1967.Crossref 9. Harber, L.C. et al: Berlocque Dermatitis , Arch Derm 90:572-576 ( (Dec) ) 1964.Crossref 10. Epstein, S.: Photoallergy and Primary Photosensitivity to Sulfanilamide , J Invest Derm 2:142-148 ( (Feb) ) 1956. 11. Sams, W.: Contact Photodermatitis , Arch Derm 73:142-148 ( (Feb) ) 1956.Crossref 12. Satulsky, E.M.: Photosensitization Induced by Monoglycerol Paraminobenzoate , Arch Derm 62:711-713 ( (Nov) ) 1950. 13. Mohajerin, A.H., and Epstein, S.: Influence of Ultraviolet Light on Patch Tests , J Invest Derm 44:213-217 ( (March) ) 1965. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Contact Photosensitivity Dermatitis From Sun-protective Agent

Archives of Dermatology , Volume 100 (4) – Oct 1, 1969

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References (13)

Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1969.01610280065011
Publisher site
See Article on Publisher Site

Abstract

Abstract A popular commercial sunscreening agent containing the ultraviolet-absorbing chemical glyceryl p-aminobenzoate was found to be a photosensitizer having produced a severe dermatitis in a patient who applied it prior to sun exposure. Three possible mechanisms of action are briefly discussed: photoallergy, phototoxicity, and photoaugmentation. The agent was shown to be an ordinary contact allergen as well as a photosensitizer. References 1. Wuepper, K.D.: Paraben Contact Dermatitis , JAMA 202:579-581 ( (Nov) ) 1967.Crossref 2. Epstein, S.: Simplified Photopatch Testing , Arch Derm 93:216-220 ( (Feb) ) 1966.Crossref 3. Epstein, S.: The Photopatch Test, Its Technique, Manifestation, and Significance , Ann Allerg 22:1-11 ( (Jan) ) 1964. 4. Shelley, W.B.: The Patch Test , JAMA 200:874-878 ( (June 5) ) 1967.Crossref 5. Fisher, A.A.: Contact Dermatitis , Philadelphia: Lea & Febiger, Publisher, 1967. 6. Baer, R.L., and Harber L.C.: Photosensitivity Induced by Drugs , JAMA 192:989-990 ( (June 14) ) 1965.Crossref 7. Jillson, O.F., and Baughman, R.D.: Contact Photodermatitis From Bithionol , Arch Derm 88:409-418 ( (Oct) ) 1963.Crossref 8. O'Quinn, S.E.; Kennedv, C.B.; and Isbell, K.H.: Contact Photodermatitis Due to Bithionol and Related Compounds . JAMA 199:89-92 ( (Jan 9) ) 1967.Crossref 9. Harber, L.C. et al: Berlocque Dermatitis , Arch Derm 90:572-576 ( (Dec) ) 1964.Crossref 10. Epstein, S.: Photoallergy and Primary Photosensitivity to Sulfanilamide , J Invest Derm 2:142-148 ( (Feb) ) 1956. 11. Sams, W.: Contact Photodermatitis , Arch Derm 73:142-148 ( (Feb) ) 1956.Crossref 12. Satulsky, E.M.: Photosensitization Induced by Monoglycerol Paraminobenzoate , Arch Derm 62:711-713 ( (Nov) ) 1950. 13. Mohajerin, A.H., and Epstein, S.: Influence of Ultraviolet Light on Patch Tests , J Invest Derm 44:213-217 ( (March) ) 1965.

Journal

Archives of DermatologyAmerican Medical Association

Published: Oct 1, 1969

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