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The Bacterial Flora of Peripheral Vascular Ulcers

The Bacterial Flora of Peripheral Vascular Ulcers Abstract A complete bacteriological study was made of skin ulcerations associated with peripheral vascular disease in 40 consecutive untreated patients, and a method of colony counting was devised. In all but five ulcers, thee was bacterial growth of at least 2,000 colonies per milliliter of water, and the total count was not well correlated with the presence or absence of clinical signs of inflammation. Staphylococcus aureus and the Enterobacteriaceae were most common in the ulcers appearing clinically inflamed whereas the indolentappearing ulcers tended to have less virulent organisms. Further work is necessary to determine whether the surface infection found in clinically inflamed ulcers is significant and warrants antibacterial therapy. References 1. Bauer, A.W.; Perry, D.M.; and Kirby, W.M.M.: Single Disc Antibiotic Sensitivity Testing of Staphylococci , Arch Inter Med 104:208-216 ( (Aug) ) 1959.Crossref 2. Collens, W.S., et al: Conservative Management of Gangrene in the Diabetic Patient , JAMA 181:692-698 ( (Aug 25) ) 1962.Crossref 3. Brentano, L., et al: Bacteriology of Large Human Burns Treated With Silver Nitrate , Arch Surg 93:456-466 ( (Sept) ) 1966.Crossref 4. Allen, E.V.; Barker, N.W.; and Hines, E.A., Jr.: Peripheral Vascular Diseases , Philadelphia: W. B. Saunders Co., 1962. 5. Ribble, J.C.: A Mechanism of Bacterial Interference in Vitro , J Immun 98:716-723 ( (April) ) 1967. 6. Sprunt, K., and Redman, W.: Evidence Suggesting Importance of Role of Interbacterial Inhibition in Maintaining Balance of Normal Flora , Ann Intern Med 68:579-590 ( (March) ) 1968.Crossref 7. Shinefield, H.R., et al: Bacterial Interference: Its Effect on Nursery Acquired Infection With Staphylococcus Aureus: III. The Georgia Epidemic , Amer J Dis Child 105:663-673 ( (June) ) 1963. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

The Bacterial Flora of Peripheral Vascular Ulcers

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References (7)

Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1969.01610250035008
Publisher site
See Article on Publisher Site

Abstract

Abstract A complete bacteriological study was made of skin ulcerations associated with peripheral vascular disease in 40 consecutive untreated patients, and a method of colony counting was devised. In all but five ulcers, thee was bacterial growth of at least 2,000 colonies per milliliter of water, and the total count was not well correlated with the presence or absence of clinical signs of inflammation. Staphylococcus aureus and the Enterobacteriaceae were most common in the ulcers appearing clinically inflamed whereas the indolentappearing ulcers tended to have less virulent organisms. Further work is necessary to determine whether the surface infection found in clinically inflamed ulcers is significant and warrants antibacterial therapy. References 1. Bauer, A.W.; Perry, D.M.; and Kirby, W.M.M.: Single Disc Antibiotic Sensitivity Testing of Staphylococci , Arch Inter Med 104:208-216 ( (Aug) ) 1959.Crossref 2. Collens, W.S., et al: Conservative Management of Gangrene in the Diabetic Patient , JAMA 181:692-698 ( (Aug 25) ) 1962.Crossref 3. Brentano, L., et al: Bacteriology of Large Human Burns Treated With Silver Nitrate , Arch Surg 93:456-466 ( (Sept) ) 1966.Crossref 4. Allen, E.V.; Barker, N.W.; and Hines, E.A., Jr.: Peripheral Vascular Diseases , Philadelphia: W. B. Saunders Co., 1962. 5. Ribble, J.C.: A Mechanism of Bacterial Interference in Vitro , J Immun 98:716-723 ( (April) ) 1967. 6. Sprunt, K., and Redman, W.: Evidence Suggesting Importance of Role of Interbacterial Inhibition in Maintaining Balance of Normal Flora , Ann Intern Med 68:579-590 ( (March) ) 1968.Crossref 7. Shinefield, H.R., et al: Bacterial Interference: Its Effect on Nursery Acquired Infection With Staphylococcus Aureus: III. The Georgia Epidemic , Amer J Dis Child 105:663-673 ( (June) ) 1963.

Journal

Archives of Dermatology – American Medical Association

Published: Jul 1, 1969

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