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Multiple Keratoacanthomas: Relation to Jamarsan Therapy of Pemphigus Foliaceus

Multiple Keratoacanthomas: Relation to Jamarsan Therapy of Pemphigus Foliaceus Abstract The eruption of multiple keratoacanthomas (KA) on the exposed areas of a patient with pemphigus foliaceus treated with the Brazilian tar preparation (Jamarsan) emphasizes the strong carcinogenic properties of the method. Two types of tumors occured on the light-exposed areas of the skin. Treatment with corticosteroids has decreased the necessity for local therapy with potential carcinogenic action. References 1. Jenkins, W.: Dermatoses Among Gas and Tar Workers , Bristol, England: John Wright and Sons, Ltd., 1949, pp 5, 24, 31. 2. Rook, A.J.; Gresham, G.A.; and Davis, R.A.: Squamous Epithelioma Possibly Induced by Therapeutic Application of Tar , Brit J Cancer 10:17-23, 1956.Crossref 3. Wickers, C.F.H., and Ghadially, F.N.: Keratoacanthoma Associated With Psoriasis , Brit J Derm 73:120-124, 1961.Crossref 4. Counter, C.E.: The Disease Called "Wildfire," Arch Derm 80:391-397, 1959.Crossref 5. Schwartz, L.; Tulipan, L.; and Birmingham, D.T.: Occupational Diseases of the Skin , Philadelphia: Lea & Febiger, 1957, pp 732. 6. de Moragas, J.M.; Montgemery, H.; and Mc Donald, J.: Keratoacanthoma Versus Squamous Cell Carcinoma , Arch Derm 77:390-395, 1958.Crossref 7. Ghadially, F.N.: The Role of the Hair Follicle in the Origin and Evolution of Some Cutaneous Neoplasms of Man and Experimental Animals , Cancer 14:801-816, 1961.Crossref 8. Hellier, F.F., and Rowell, N.R.: Giant Keratoacanthoma Complicating Dermatitis , Arch Derm 85:485-487, 1962.Crossref 9. Bessiere, L.: Keratoacanthoma et xeroderma pigmentosum , Bull Soc Franc Derm Syph 67:1012-1013, 1960. 10. Whittle, V.H., and Davis, R.A.: Keratoacanthoma , Lancet 272:1019-1020, 1957.Crossref 11. Friedenwald, W.F., and Rous, P.: The Initiating and Promoting Elements in Tumor Production: An Analysis of the Effects of Tar, Benzopyrene and Methylcholantrene on Rabbit Skin , J Exp Med 80:101-126, 1944.Crossref 12. Blum, H.F.: Carcinogenesis by Ultraviolet Light , Princeton, NJ: Princeton University Press, 1959. 13. Orr, J.W.: The Role of the Stroma in Epidermal Carcinogenesis , Nat Cancer Inst Monogr 10:531, 1963. 14. Winkelmann, R.K.; Zollman, R.E.; and Baldes, E.J.: Squamous Cell Carcinoma Produced by Ultraviolet Light in Hairless Mice , J Invest Derm 40:217-224, 1963. 15. Shubik, P.: A Comparison of Different Methods of Skin Carcinogenesis and Reflections of the Two Stages Hypothesis , Acta Un Int Cancr 17:24-31, 1961. 16. Shubik, P.: The Growth Potentialities of Induced Skin Tumors in Mice: The Effects of Different Methods of Chemical Carcinogenesis , Cancer Res 10:713-717, 1959. 17. Rocha, G.: In Brunsting, L.A., et al: Case 12: Pemphigus Foliaceus, Society Transactions , Arch Derm 85:678-679, 1962. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Multiple Keratoacanthomas: Relation to Jamarsan Therapy of Pemphigus Foliaceus

DE MORAGAS, JOSE M.
Archives of Dermatology , Volume 93 (6) – Jun 1, 1966
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References (20)

Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1966.01600240045008
Publisher site
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Abstract

Abstract The eruption of multiple keratoacanthomas (KA) on the exposed areas of a patient with pemphigus foliaceus treated with the Brazilian tar preparation (Jamarsan) emphasizes the strong carcinogenic properties of the method. Two types of tumors occured on the light-exposed areas of the skin. Treatment with corticosteroids has decreased the necessity for local therapy with potential carcinogenic action. References 1. Jenkins, W.: Dermatoses Among Gas and Tar Workers , Bristol, England: John Wright and Sons, Ltd., 1949, pp 5, 24, 31. 2. Rook, A.J.; Gresham, G.A.; and Davis, R.A.: Squamous Epithelioma Possibly Induced by Therapeutic Application of Tar , Brit J Cancer 10:17-23, 1956.Crossref 3. Wickers, C.F.H., and Ghadially, F.N.: Keratoacanthoma Associated With Psoriasis , Brit J Derm 73:120-124, 1961.Crossref 4. Counter, C.E.: The Disease Called "Wildfire," Arch Derm 80:391-397, 1959.Crossref 5. Schwartz, L.; Tulipan, L.; and Birmingham, D.T.: Occupational Diseases of the Skin , Philadelphia: Lea & Febiger, 1957, pp 732. 6. de Moragas, J.M.; Montgemery, H.; and Mc Donald, J.: Keratoacanthoma Versus Squamous Cell Carcinoma , Arch Derm 77:390-395, 1958.Crossref 7. Ghadially, F.N.: The Role of the Hair Follicle in the Origin and Evolution of Some Cutaneous Neoplasms of Man and Experimental Animals , Cancer 14:801-816, 1961.Crossref 8. Hellier, F.F., and Rowell, N.R.: Giant Keratoacanthoma Complicating Dermatitis , Arch Derm 85:485-487, 1962.Crossref 9. Bessiere, L.: Keratoacanthoma et xeroderma pigmentosum , Bull Soc Franc Derm Syph 67:1012-1013, 1960. 10. Whittle, V.H., and Davis, R.A.: Keratoacanthoma , Lancet 272:1019-1020, 1957.Crossref 11. Friedenwald, W.F., and Rous, P.: The Initiating and Promoting Elements in Tumor Production: An Analysis of the Effects of Tar, Benzopyrene and Methylcholantrene on Rabbit Skin , J Exp Med 80:101-126, 1944.Crossref 12. Blum, H.F.: Carcinogenesis by Ultraviolet Light , Princeton, NJ: Princeton University Press, 1959. 13. Orr, J.W.: The Role of the Stroma in Epidermal Carcinogenesis , Nat Cancer Inst Monogr 10:531, 1963. 14. Winkelmann, R.K.; Zollman, R.E.; and Baldes, E.J.: Squamous Cell Carcinoma Produced by Ultraviolet Light in Hairless Mice , J Invest Derm 40:217-224, 1963. 15. Shubik, P.: A Comparison of Different Methods of Skin Carcinogenesis and Reflections of the Two Stages Hypothesis , Acta Un Int Cancr 17:24-31, 1961. 16. Shubik, P.: The Growth Potentialities of Induced Skin Tumors in Mice: The Effects of Different Methods of Chemical Carcinogenesis , Cancer Res 10:713-717, 1959. 17. Rocha, G.: In Brunsting, L.A., et al: Case 12: Pemphigus Foliaceus, Society Transactions , Arch Derm 85:678-679, 1962.

Journal

Archives of Dermatology – American Medical Association

Published: Jun 1, 1966

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