Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Inverted Follicular Keratosis

Inverted Follicular Keratosis Abstract Helwig's inverted follicular keratosis is a benign epithelial tumor appearing most commonly as a single lesion on the face of patients in the older age group. It is characterized by distinct histologic features. After careful study of 40 cases, I am inclined to agree with Duperrat and Mascaro that these tumors are closely related to the infundibulum of the hair follicle and are an analogue of eccrine poroma which is generally accepted as a tumor of the intraepidermal sweat duct unit. Histologic points supporting this idea are presented, and a comparison with eccrine poroma is made. References 1. Helwig, E. B.: " Inverted Follicular Keratosis ," in Seminar on the Skin: Neoplasms and Dermatoses, American Society of Clinical Pathologists, International Congress of Clinical Pathology, Washington, DC, September, 1954 ; published by American Society of Clinical Pathology, 1955. 2. Braun-Falco, O., and Kint, A.: Zur Histogenese der Verruca Seborrheica: I , Arch Klin Exp Derm 216: 615-649, 1963.Crossref 3. Mehregan, A. H., and Pinkus, H.: Intraepidermal Epithelioma: a Critical Study , Cancer , to be published. 4. Mishima, Y., and Mevorah, B.: Seborrheic Keratosis: Experimentally Induced Cellular Changes, and Its Electron Microscopy, in preparation. 5. Lund, H. Z.: Atlas of Tumor Pathology: Tumors of the Skin , Section 1 , Fascicle (2) , Washington, DC: Armed Forces Institute of Pathology, 1957. 6. Becker, W. S.: Seborrheic Keratosis and Verruca, With Special Reference to the Melanotic Variety , AMA Arch Derm Syph 63:358-372, 1951.Crossref 7. Rowe, L.: Seborrheic Keratoses: 1. "Pseudoepitheliomatous Hyperplasia" (Weidman) , J Invest Derm 29:165-180, 1957.Crossref 8. Pinkus, H.: Four-Dimensional Histopathology , Arch Derm 82:681-689, 1960.Crossref 9. Boniuk, M., and Zimmerman, L. E.: Eyelid Tumors With Reference to Lesions Confused With Squamous Cell Carcinoma: II. Inverted Follicular Keratosis , Arch Ophthal 69:698-707, 1963.Crossref 10. Duperrat, B., et Mascaro, J. M.: Une tumeur benigne developpée aux depens de l'acrotrichium ou partie intraépidermique du follicule pilaire: Porome folliculaire (acanthome folliculaire intraépidermique; acrotrichoma) , Dermatologica 126:291-310, 1963.Crossref 11. Pinkus, H.; Rogin, J. R.; and Goldman, P.: Eccrine Poroma, Tumors Exhibiting Features of the Epidermal Sweat Duct Unit , AMA Arch Derm 74:511-521, 1956.Crossref 12. Pinkus, H.: " Embryology of Hair ," in Montagna, W., and Ellis, R. A.: The Biology of Hair Growth , New York: Academic Press, Inc., 1958. 13. Pinkus, H.: Keratosis Senilis: A Biologic Concept of Its Pathogenesis and Diagnosis Based on the Study of Normal Epidermis and 1,730 Seborrheic and Senile Keratoses , Amer J Clin Path 29:193-207, 1958. 14. Mehregan, A. H., and Butler, J. D.: A Tumor of Follicular Infundibulum , Arch Derm 83:924-927, 1961.Crossref 15. Kligman, A. M., and Pinkus, H.: The Histogenesis of Nevoid Tumors of the Skin , AMA Arch Derm 81:922-930, 1960.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Inverted Follicular Keratosis

Archives of Dermatology , Volume 89 (2) – Feb 1, 1964

Loading next page...
 
/lp/american-medical-association/inverted-follicular-keratosis-ZONCp6cJXS

References (18)

Publisher
American Medical Association
Copyright
Copyright © 1964 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1964.01590260067012
Publisher site
See Article on Publisher Site

Abstract

Abstract Helwig's inverted follicular keratosis is a benign epithelial tumor appearing most commonly as a single lesion on the face of patients in the older age group. It is characterized by distinct histologic features. After careful study of 40 cases, I am inclined to agree with Duperrat and Mascaro that these tumors are closely related to the infundibulum of the hair follicle and are an analogue of eccrine poroma which is generally accepted as a tumor of the intraepidermal sweat duct unit. Histologic points supporting this idea are presented, and a comparison with eccrine poroma is made. References 1. Helwig, E. B.: " Inverted Follicular Keratosis ," in Seminar on the Skin: Neoplasms and Dermatoses, American Society of Clinical Pathologists, International Congress of Clinical Pathology, Washington, DC, September, 1954 ; published by American Society of Clinical Pathology, 1955. 2. Braun-Falco, O., and Kint, A.: Zur Histogenese der Verruca Seborrheica: I , Arch Klin Exp Derm 216: 615-649, 1963.Crossref 3. Mehregan, A. H., and Pinkus, H.: Intraepidermal Epithelioma: a Critical Study , Cancer , to be published. 4. Mishima, Y., and Mevorah, B.: Seborrheic Keratosis: Experimentally Induced Cellular Changes, and Its Electron Microscopy, in preparation. 5. Lund, H. Z.: Atlas of Tumor Pathology: Tumors of the Skin , Section 1 , Fascicle (2) , Washington, DC: Armed Forces Institute of Pathology, 1957. 6. Becker, W. S.: Seborrheic Keratosis and Verruca, With Special Reference to the Melanotic Variety , AMA Arch Derm Syph 63:358-372, 1951.Crossref 7. Rowe, L.: Seborrheic Keratoses: 1. "Pseudoepitheliomatous Hyperplasia" (Weidman) , J Invest Derm 29:165-180, 1957.Crossref 8. Pinkus, H.: Four-Dimensional Histopathology , Arch Derm 82:681-689, 1960.Crossref 9. Boniuk, M., and Zimmerman, L. E.: Eyelid Tumors With Reference to Lesions Confused With Squamous Cell Carcinoma: II. Inverted Follicular Keratosis , Arch Ophthal 69:698-707, 1963.Crossref 10. Duperrat, B., et Mascaro, J. M.: Une tumeur benigne developpée aux depens de l'acrotrichium ou partie intraépidermique du follicule pilaire: Porome folliculaire (acanthome folliculaire intraépidermique; acrotrichoma) , Dermatologica 126:291-310, 1963.Crossref 11. Pinkus, H.; Rogin, J. R.; and Goldman, P.: Eccrine Poroma, Tumors Exhibiting Features of the Epidermal Sweat Duct Unit , AMA Arch Derm 74:511-521, 1956.Crossref 12. Pinkus, H.: " Embryology of Hair ," in Montagna, W., and Ellis, R. A.: The Biology of Hair Growth , New York: Academic Press, Inc., 1958. 13. Pinkus, H.: Keratosis Senilis: A Biologic Concept of Its Pathogenesis and Diagnosis Based on the Study of Normal Epidermis and 1,730 Seborrheic and Senile Keratoses , Amer J Clin Path 29:193-207, 1958. 14. Mehregan, A. H., and Butler, J. D.: A Tumor of Follicular Infundibulum , Arch Derm 83:924-927, 1961.Crossref 15. Kligman, A. M., and Pinkus, H.: The Histogenesis of Nevoid Tumors of the Skin , AMA Arch Derm 81:922-930, 1960.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Feb 1, 1964

There are no references for this article.