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NEW YORK DERMATOLOGICAL SOCIETY

NEW YORK DERMATOLOGICAL SOCIETY This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Letterer-Siwe Disease (Malignant, Nonlipid Reticuloendotheliosis). Presented by Dr. George C. Anderews. History.— The patients were 8-month-old white male infants, identical twins. At the age of 4 months, both developed a skin eruption which persisted in spite of local use of steroids. There were involvement of the scalp consisting of a dry, scaly eruption which looked like "cradle cap" and also involvement of the mouth.They developed "ear infections" which cleared up after a while on antibiotics. Physical Examination.— On physical examination both infants present more or less the same clinical picture. The scalp is involved with a yellowish-brown crust which simulates seborrheic dermatitis. The skin, especially trunk and abdomen, presents a reddish-brown to orange-colored papular scaly eruption. Some of the papules look hemorrhagic; others are like xanthoma. Some are petechiae. There are small ulcerations in the oral mucosa.There is no lymphadenopathy, and spleen and liver cannot be palpated. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

NEW YORK DERMATOLOGICAL SOCIETY

Archives of Dermatology , Volume 85 (6) – Jun 1, 1962

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Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1962.01590060122024
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Letterer-Siwe Disease (Malignant, Nonlipid Reticuloendotheliosis). Presented by Dr. George C. Anderews. History.— The patients were 8-month-old white male infants, identical twins. At the age of 4 months, both developed a skin eruption which persisted in spite of local use of steroids. There were involvement of the scalp consisting of a dry, scaly eruption which looked like "cradle cap" and also involvement of the mouth.They developed "ear infections" which cleared up after a while on antibiotics. Physical Examination.— On physical examination both infants present more or less the same clinical picture. The scalp is involved with a yellowish-brown crust which simulates seborrheic dermatitis. The skin, especially trunk and abdomen, presents a reddish-brown to orange-colored papular scaly eruption. Some of the papules look hemorrhagic; others are like xanthoma. Some are petechiae. There are small ulcerations in the oral mucosa.There is no lymphadenopathy, and spleen and liver cannot be palpated.

Journal

Archives of DermatologyAmerican Medical Association

Published: Jun 1, 1962

There are no references for this article.