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H. Hurley, G. Koelle (1958)
The effect of inhibition of non-specific cholinesterase on perception of tactile sensation in human volar skin.The Journal of investigative dermatology, 31 4
F. Recklinghausen
Ueber die multiplen Fibrome der Haut und ihre Beziehung zu den multiplen Neuromen
R. Winkelmann, R. Schmit (1959)
Cholinesterases in human skin.Archives of dermatology, 80
W. Penfield (1932)
TUMORS OF THE SHEATHS OF THE NERVOUS SYSTEMJournal of Nervous and Mental Disease, 27
M. Murray, A. Stout (1947)
Distinctive Characteristics of the Sympathicoblastoma Cultivated in Vitro: A Method for Prompt Diagnosis.The American journal of pathology, 23 3
G. Koelle, Helga Wagner (1955)
The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons.The Journal of pharmacology and experimental therapeutics, 114 2
R. K. Winkelmann (1961)
The Skin as a Sensory OrganJ. Soc. Cosmetic Chem., 12
A. Pearse (1953)
Histochemistry: Theoretical and AppliedMedical Journal of Australia, 1
R. K. Winkelmann (1959)
Cholinesterases in Human SkinA.M.A. Arch. Derm., 80
R. Winkelmann (1960)
Cholinesterase nevus: cholinesterases in pigmented tumors of the skin.Archives of dermatology, 82
R. Winkelmann (1960)
Nerve endings in normal and pathologic skin : contributions to the anatomy of sensation
(1949)
National Research Council, Committee on Pathology: Atlas of Tumor Pathology
I. M. Tarlov (1940)
Origin of the Perineural FibroblastomaAmer. J. Path., 16
W. Penfield (1932)
Tumors of the Sheaths of the Nervous SystemArch. Neurol. Psychiat., 27
W. Lever (1962)
Histopathology of the SkinThe American Journal of the Medical Sciences, 243
R. Winkelmann (1960)
Cholinesterase in the cutaneous nevusCancer, 13
R. Winkelmann, R. Schmit (1959)
Cholinesterase in the skin of the rat, dog, cat, guinea pig and rabbit.The Journal of investigative dermatology, 33
Abstract Cholinesterase is an enzyme associated with neural tissue. It has been demonstrated chemically and histochemically in sensory and motor tissue of the central nervous system, the myoneural junction, and the sensory end-organs.1 Specific cholinesterase, which hydrolyzes acetylcholine and acetylbetamethylcholine (methacholine), is found in autonomic nerve structures in the skin. Nonspecific (pseudo) cholinesterase, which hydrolyzes long-chain aliphatic acid esters of choline and benzoylcholine, is found in the cutaneous sensory end-organs. A group of inhibiting substances may be used to distinguish further the specific and nonspecific reactions. These may block either or both reactions, as described by Pearse.2 It has been our practice to use those inhibitors that seem best suited to the tissue being studied. Our recent experience has been with NU 683* and 62C47,† and these have proved satisfactory. It is possible to define with reasonable accuracy the type of cholinesterase activity present in a given tissue by References 1. Trimethyl-(2-dimethylcarbamyloxy-5-phenyl)-benzylammonium bromide. 2. A cholinesterase inhibitor. 3. Koelle, G. B.: The Histochemical Identification of Acetylcholinesterase in Cholinergic, Adrenergic, and Sensory Neurons , J. Pharmacol. Exp. Ther. 114:167-184 ( (June) ) 1955. 4. Pearse, A. G. E.: Histochemistry, Theoretical and Applied , Ed. 2, Boston, Little, Brown & Company, 1960, 998 pp. 5. Winkelmann, R. K.: The Skin as a Sensory Organ , J. Soc. Cosmetic Chem. 12:80-89 ( (Feb.) ) 1961. 6. Winkelmann, R. K.: Nerve Endings in Normal and Pathologic Skin: Contributions to the Anatomy of Sensation , American Lecture Series Monograph, Springfield, Ill., Charles C Thomas, Publisher, 1960, 300 pp. 7. Hurley, H. J., and Koelle, G. B.: The Effect of Inhibition of Non-Specific Cholinesterase on Perception of Tactile Sensation in Human Volar Skin , J. Invest. Derm. 31:243-245 ( (Oct.) ) 1958.Crossref 8. Winkelmann, R. K.: The Effect of Sciatic-Nerve Section on Histochemical Reactions of Sensory End-Organs, unpublished data. 9. Winkelmann, R. K.: Cholinesterase Nevus: Cholinesterase in Pigmented Tumors of the Skin , Arch. Derm. 82:17-23 ( (July) ) 1960.Crossref 10. Winkelmann, R. K.: Cholinesterase in the Cutaneous Nevus , Cancer 13:626-630 ( (May) -June) 1960.Crossref 11. Winkelmann, R. K., and Schmidt, R. W.: Cholinesterases in Human Skin , A.M.A. Arch. Derm. 80:543-548 ( (Nov.) ) 1959.Crossref 12. Winkelmann, R. K., and Schmidt, R. W.: Cholinesterase in the Skin of the Rat, Dog, Cat, Guinea Pig, and Rabbit , J. Invest. Derm. 33:185-190 ( (Oct.) ) 1959.Crossref 13. von Recklinghausen, F. D.: Ueber die multiplen Fibrome der Haut und ihre Beziehung zu den multiplen Neuromen , Berlin, A. Hirschwald, 1882, 144 pp. 14. Penfield, W.: Tumors of the Sheaths of the Nervous System , Arch. Neurol. Psychiat. 27: 1298-1309 ( (July) ) 1932.Crossref 15. Tarlov, I. M.: Origin of the Perineural Fibroblastoma , Amer. J. Path. 16:33-40 ( (Jan.) ) 1940. 16. Murray, M. R., and Stout, A. P.: Distinctive Characteristics of the Sympathicoblastoma Cultivated in Vitro: A Method for Prompt Diagnosis , Amer. J. Path. 23:429-442 ( (May) ) 1947. 17. Tumors of the Peripheral Nervous System , in National Research Council, Committee on Pathology: Atlas of Tumor Pathology , Washington, D.C., Armed Forces Institute of Pathology, Section II, (Fascicle 6) , 1949. 18. Lever, W. F.: Histopathology of the Skin , Ed. 2, Philadelphia, J. B. Lippincott Company, 1954, 518 pp.
Archives of Dermatology – American Medical Association
Published: Jan 1, 1962
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