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Triamcinolone Acetonide in the Treatment of Oral Mucous Membrane Lesions: II. Continued Studies Using a Powder Adhesive Vehicle

Triamcinolone Acetonide in the Treatment of Oral Mucous Membrane Lesions: II. Continued Studies... Abstract A previous study of the usefulness of triamcinolone acetonide (Kenalog) in the treatment of acute and chronic lesions of the oral mucous membranes has been reported.* After considerable experience with triamcinolone acetonide in Orabase (an adhesive paste vehicle), it became evident that although this formulation was effective in treating lesions up to 1 cc. in diameter, many patients found it difficult to spread the paste material evenly or to apply it as a thin film over larger lesions, particularly those in certain difficult to reach oral sites or those in almost totally inaccessible regions such as the uvula and adjacent areas, the anterior fauces, and the base of the tongue. It was for these reasons that we investigated the possibilities of using a powder adhesive formulation (rather than a paste vehicle) of triamcinolone acetonide in the treatment of similar and additional lesions of the oral cavity. Orahesive, a name applied References 1. Triamcinolone acetonide (Kenalog) in a new adhesive vehicle (Orahesive) was supplied by The Squibb Institute for Medical Research, New Brunswick, N.J. 2. Zegarelli, E. V.; Kutscher, A. H.; Silvers, H. F.; Beube, F. E.; Stern, I. B.; Berman, C. L., and Herlands, R. E.: Triamcinolone Acetonide in the Treatment of Acute and Chronic Lesions of the Oral Mucous Membranes: Preliminary Report , Oral Surg. 13:170 ( (Feb.) ) 1960.Crossref 3. Kutscher, A. H., and Zegarelli, E. V.: A New Adhesive Protectant Vehicle for Oral Mucosal Disease , Arch. Derm. 82:624 ( (Oct.) ) 1960.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Triamcinolone Acetonide in the Treatment of Oral Mucous Membrane Lesions: II. Continued Studies Using a Powder Adhesive Vehicle

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References (2)

Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1961.01580180151029
Publisher site
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Abstract

Abstract A previous study of the usefulness of triamcinolone acetonide (Kenalog) in the treatment of acute and chronic lesions of the oral mucous membranes has been reported.* After considerable experience with triamcinolone acetonide in Orabase (an adhesive paste vehicle), it became evident that although this formulation was effective in treating lesions up to 1 cc. in diameter, many patients found it difficult to spread the paste material evenly or to apply it as a thin film over larger lesions, particularly those in certain difficult to reach oral sites or those in almost totally inaccessible regions such as the uvula and adjacent areas, the anterior fauces, and the base of the tongue. It was for these reasons that we investigated the possibilities of using a powder adhesive formulation (rather than a paste vehicle) of triamcinolone acetonide in the treatment of similar and additional lesions of the oral cavity. Orahesive, a name applied References 1. Triamcinolone acetonide (Kenalog) in a new adhesive vehicle (Orahesive) was supplied by The Squibb Institute for Medical Research, New Brunswick, N.J. 2. Zegarelli, E. V.; Kutscher, A. H.; Silvers, H. F.; Beube, F. E.; Stern, I. B.; Berman, C. L., and Herlands, R. E.: Triamcinolone Acetonide in the Treatment of Acute and Chronic Lesions of the Oral Mucous Membranes: Preliminary Report , Oral Surg. 13:170 ( (Feb.) ) 1960.Crossref 3. Kutscher, A. H., and Zegarelli, E. V.: A New Adhesive Protectant Vehicle for Oral Mucosal Disease , Arch. Derm. 82:624 ( (Oct.) ) 1960.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Dec 1, 1961

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