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Fungistatic and Fungicidal Tests with Ethyl Alcohol

Fungistatic and Fungicidal Tests with Ethyl Alcohol Abstract In a previous unreported experiment* the antifungal effect of 10% Lysol (disinfectant with orthophenylphenol as principal germicidal ingredient) was compared with several dilutions of two different soaps, the common domestic "Offenbach" and the antiseptic "Nobater" (Laboratories Chantereau, Arcueil, Seine). Using a technique described by Frey et al.,1 Lysol showed fungicidal effect in vitro against Trichophyton violaceum, T. tonsurans, T. mentagrophytes, T. schoenleinii, T. megninii, and Microsporum canis. Dilutions of both soaps at 1/1,000, 1/100, and 1/10 did not inhibit growth of the same dermatophytes. As pointed out recently2 there are very few references reporting the effect of ethyl alcohol on the normal growth of dermatophytes. In 1933, Emmons3 reported that T. gypseum was not inhibited after 30 minutes' immersion in 50% alcohol but did not develop after 30 minutes in 85% alcohol. Loewenthal4 has just studied the effect of 70% ethyl alcohol on hairs infected by References 1. Performed in the Mycology Laboratory Department of Dermatology of Faculty of Medicine, University of Lisbon, Portugal. 2. Frey, J. R.; Wenk, P., and Fust, B.: Nuevos metodos para el ensayo de antimicoticos "in vitro" y "in vivo ," Rev. Argent. Dermatosif. 38:93-113, 1954. 3. Fungicidal Action of Alcohol, Questions and Answers , J.A.M.A. 172:1116, 1960.Crossref 4. Emmons, C. W.: Fungicidal Action of Some Common Disinfectants on 2 Dermatophytes , Arch. Derm. Syph. 28:15-21, 1933.Crossref 5. Loewenthal, K.: The Antifungal Effect of 70% Ethyl Alcohol , A.M.A. Arch. Derm. 83:803-805, 1961.Crossref 6. Roth, F. J., Jr.; Boyd, C. C.; Sagami, S., and Blank, H.: An Evaluation of the Fungistatic Activity of Serum , J. Invest. Derm. 32:549-556, 1959.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Fungistatic and Fungicidal Tests with Ethyl Alcohol

NEVES, HERMANO
Archives of Dermatology , Volume 84 (5) – Nov 1, 1961
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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1961.01580170084010
Publisher site
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Abstract

Abstract In a previous unreported experiment* the antifungal effect of 10% Lysol (disinfectant with orthophenylphenol as principal germicidal ingredient) was compared with several dilutions of two different soaps, the common domestic "Offenbach" and the antiseptic "Nobater" (Laboratories Chantereau, Arcueil, Seine). Using a technique described by Frey et al.,1 Lysol showed fungicidal effect in vitro against Trichophyton violaceum, T. tonsurans, T. mentagrophytes, T. schoenleinii, T. megninii, and Microsporum canis. Dilutions of both soaps at 1/1,000, 1/100, and 1/10 did not inhibit growth of the same dermatophytes. As pointed out recently2 there are very few references reporting the effect of ethyl alcohol on the normal growth of dermatophytes. In 1933, Emmons3 reported that T. gypseum was not inhibited after 30 minutes' immersion in 50% alcohol but did not develop after 30 minutes in 85% alcohol. Loewenthal4 has just studied the effect of 70% ethyl alcohol on hairs infected by References 1. Performed in the Mycology Laboratory Department of Dermatology of Faculty of Medicine, University of Lisbon, Portugal. 2. Frey, J. R.; Wenk, P., and Fust, B.: Nuevos metodos para el ensayo de antimicoticos "in vitro" y "in vivo ," Rev. Argent. Dermatosif. 38:93-113, 1954. 3. Fungicidal Action of Alcohol, Questions and Answers , J.A.M.A. 172:1116, 1960.Crossref 4. Emmons, C. W.: Fungicidal Action of Some Common Disinfectants on 2 Dermatophytes , Arch. Derm. Syph. 28:15-21, 1933.Crossref 5. Loewenthal, K.: The Antifungal Effect of 70% Ethyl Alcohol , A.M.A. Arch. Derm. 83:803-805, 1961.Crossref 6. Roth, F. J., Jr.; Boyd, C. C.; Sagami, S., and Blank, H.: An Evaluation of the Fungistatic Activity of Serum , J. Invest. Derm. 32:549-556, 1959.Crossref

Journal

Archives of Dermatology – American Medical Association

Published: Nov 1, 1961

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