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L. River, J. Silverstein, J. Tope (1956)
Benign neoplasms of the small intestine; a critical comprehensive review with reports of 20 new cases.Surgery, gynecology & obstetrics, 102 1
Foraker Ag, Wingo Wj (1956)
Protein bound sulfhydryl and disulfide groups and succinic dehydrogenase activity in basal cell carcinoma of the skin.Experimental medicine and surgery, 14
M. Singer, G. Wislocki (1948)
The affinity of syncytium, fibrin and fibrinoid of the human placenta for acid and basic dyes under controlled conditions of stainingThe Anatomical Record, 102
S. Rothman (1954)
Physiology and biochemistry of the skin
A. Foraker, J. Reagan (1956)
Nuclear size and nuclear: Cytoplasmic ratio in the delineation of atypical hyperplasia of the uterine cervixCancer, 9
A. Foraker, S. Denham (1957)
Squamous-cell carcinoma of the uterine cervix; a histochemical review.American journal of obstetrics and gynecology, 74 1
C. Leuchtenberger (1957)
General Cytochemical Methods, 1
R. Wheatley, A. Foraker (1960)
Protein characterization in normal and abnormal cervical squamous mucosa--"pH signature".American journal of obstetrics and gynecology, 80
A. Foraker, J. Reagan (1959)
Nuclear mass and allied phenomena in normal exocervical mucosa, squamous metaplasia, atypical hyperplasia, intraepithelial carcinoma, and invasive squamous cell carcinoma of the uterine cervixCancer, 12
A. G. Foraker (1952)
Analysis of Hyperchromatism in the Histologic Diagnosis of Carcinoma of the Cervix UteriA.M.A. Arch. Path., 53
C. Leuchtenberger (1958)
Quantitative determination of DNA in cells by Feulgen microspectrophotometry.General cytochemical methods, 1
A. G. Foraker (1955)
Histochemical Studies of SkinA.M.A. Arch. Dermat., 17
A. Foraker (1956)
Histochemical studies in squamous carcinomaCancer, 9
A. G. Foraker (1956)
A Histochemical Study of Breast CarcinomaSurg. Gynec. & Obst., 102
N. Kurnick (1955)
Histochemistry of Nucleic AcidsInternational Review of Cytology-a Survey of Cell Biology, 4
R. J. Barrnett (1957)
Histochemistry (Manual of Post-graduate Medical Study)
C. Leuchtenberger, R. Leuchtenberger, A. Davis (1954)
A microspectrophotometric study of the desoxyribose nucleic acid (DNA) content in cells of normal and malignant human tissues.The American journal of pathology, 30 1
M. Singer (1952)
Factors Which Control the Staining of Tissue Sections with Acid and Basic DyesInternational Review of Cytology-a Survey of Cell Biology, 1
E. Dempsey, M. Singer (1946)
Observations on the chemical cytology of the thyroid gland at different functional stages.Endocrinology, 38
A. G. Foraker (1960)
"pH Signature" of Adenocarcinoma of Colon in ManJ. Histochem., 8
J. Brachet (1957)
Biochemical Cytology
A. G. Foraker (1956)
Estudios bioquimicos en el condrosarcomaFolia Clín. Internac., 6
R. E. Wheatley (1960)
"pH Signature" Studies in Squamous Mucosa of the Uterine Cervix: Normal Exocervical, Metaplastic, Dysplastic, Intraepithelial and Invasive CarcinomatousAm. J. Obst. & Gynec., 80
K. Steiner (1959)
A Histochemical Study of HyperkeratosesA.M.A. Arch. Dermat., 79
A. Foraker, W. Wingo (1956)
Senile and seborrheic keratoses; localization of succinic dehydrogenase, protein-bound sulfhydryl, and disulfide groups.The American journal of pathology, 32 3
A. Foraker, W. Wingo (1955)
Succinic dehydrogenase activity, protein bound sulfhydryl and disulfide groups in squamous cell carcinoma of the skin.Surgery, gynecology & obstetrics, 101 3
E. D. P. De Robertis , W. W. Nowinski (1954)
General Cytology
Abstract Comparisons of microscopic pattern of neoplastic and non-neoplastic cells are of daily practical importance in the diagnosis of tumors and the management of cancer patients. Comparisons of chemical pattern are still largely in the field of research1 but are an essential step in furthering our understanding of neoplasia.2 For some years we3 have been applying new cell techniques developed by histochemists and cytophysicists to the study of human cancer. One technique of considerable potential is the "pH signature."4,5 Proteins differ according to the nature and number of their constituent amino acids and conjugated substances.6 Proteins are amphoteric. They contain at the same time both basic and acidic groups, which, by their dissociation, give rise to positive and negative charges on the protein molecule. The ability of proteins to take up acid or basic dye according to the pH of the solution is an expression of References 1. Foraker, A. G., and Wingo, W. J.: Succinic Dehydrogenase Activity, Protein Bound Sulfhydryl and Disulfide Groups in Squamous Cell Carcinoma of the Skin , Surg. Gynec. & Obst. 101:346-352, 1955. 2. Foraker, A. G.: A Histochemical Study of Breast Carcinoma , Surg. Gynec. & Obst. 102:1-8, 1956. 3. Foraker, A. G., and Denham, S. W.: Squamous Cell Carcinoma of the Uterine Cervix: A Histochemical Review , Am. J. Obst. & Gynec. 74: 13-24, 1959. 4. Dempsey, E. W., and Singer, M.: Observations on the Chemical Cytology of the Thyroid Gland at Different Functional Stages , Endocrinology 38:270-295, 1946. 5. Singer, M., and Wislocki, G. B.: Affinity of Syncytium, Fibrin and Fibrinoid of Human Placenta for Acid and Basic Dyes Under Controlled Conditions of Staining , Anat. Rec. 102: 175-193, 1948. 6. Singer, M.: Factors Which Control the Staining of Tissue Sections with Acid and Basic Dyes , Int. Rev. Cytol. 1:211-255, 1952. 7. Barrnett, R. J.: Personal communication to the author. 8. Barrnett, R. J.: Histochemical Demonstration of Proteins , in Histochemistry (Manual of Post-graduate Medical Study) , (June 10) -22, 1957, University of Kansas School of Medicine, Kansas City, Kan. 9. De Robertis, E. D. P.; Nowinski, W. W., and Saez, F. A.: General Cytology , Ed. 2, Philadelphia, W. B. Saunders Company, 1954. 10. Kurnick, N. B.: Histochemistry of Nucleic Acids , Int. Rev. Cytol. 4:221-268, 1955. 11. Leuchtenberger, C.; Leuchtenberger, R., and Davis, A. M.: A Microspectrophotometric Study of the Desoxyribose Nucleic Acid (DNA) Content in Cells of Normal and Malignant Human Tissues , Am. J. Path. 30:65-85, 1954. 12. Singer, M.: Personal communication to the author. 13. Wheatley, R. E., and Foraker, A. G.: "pH Signature" Studies in Squamous Mucosa of the Uterine Cervix: Normal Exocervical, Metaplastic, Dysplastic, Intraepithelial and Invasive Carcinomatous , Am. J. Obst. & Gynec. 80:1074-1082, 1960. 14. Foraker, A. G.: "pH Signature" of Adenocarcinoma of Colon in Man , J. Histochem. 8: 284-289, 1960. 15. Brachet, J.: Biochemical Cytology , New York, Academic Press, Inc., 1957, p. 179. 16. Leuchtenberger, C.: Quantitative Determination of DNA in Cells by Feulgen Microspectrophotometry , in General Cytochemical Methods , edited by G. H. Bourne and J. F. Danielli, New York, Academic Press, Inc., 1957, Vol. 1, p. 220-278. 17. Rothman, S.: Physiology and Biochemistry of the Skin , Chicago, The University of Chicago Press, 1954. 18. Foraker, A. G., and Wingo, W. J.: Histochemical Studies of Skin , A.M.A. Arch. Dermat. 17:1-6, 1955. 19. Foraker, A. G., and Wingo, W. J.: Protein Bound Sulfhydryl and Disulfide Groups and Succinic Dehydrogenase Activity in Basal Cell Carcinoma of the Skin , Exper. Med. & Surg. 14: 122-129, 1956. 20. Foraker, A. G., and Wingo, W. J.: Senile and Seborrheic Keratoses: Localization of Succinic Dehydrogenase, Protein Bound Sulfhydryl and Disulfide Groups , Am. J. Path. 32:521-533, 1956. 21. Foraker, A. G.: Histochemical Studies in Squamous Carcinoma , Cancer 9:367-373, 1956. 22. Steiner, K.: A Histochemical Study of Hyperkeratoses , A.M.A. Arch. Dermat. 79:436-443, 1959. 23. Foraker, A. G., and Marino, G.: Estudios bioquimicos en el condrosarcoma , Folia Clín. Internac. 6:56-60, 1956. 24. Foraker, A. G.: Analysis of Hyperchromatism in the Histologic Diagnosis of Carcinoma of the Cervix Uteri , A.M.A. Arch. Path. 53:250-256, 1952. 25. Foraker, A. G., and Reagan, J. W.: Nuclear Size and Nuclear: Cytoplasmic Ratio in the Delineation of Atypical Hyperplasia of the Uterine Cervix , Cancer 9:470-479, 1956. 26. Foraker, A. G., and Reagan, J. W.: Nuclear Mass and Allied Phenomena in Normal Exocervical Mucosa, Squamous Metaplasia, Atypical Hyperplasia, Intraepithelial Carcinoma and Invasive Squamous Cell Carcinoma of the Uterine Cervix , Cancer 12:894-905, 1959.
Archives of Dermatology – American Medical Association
Published: Mar 1, 1961
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