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J. Jacobs (1956)
Rheumatoid Arthritis and Psoriasis VulgarisAnnals of the Rheumatic Diseases, 15
R. R. H. Lovell , D. M. Pryce (1954)
The Necrotic Lesions in Guinea-Pig Skin Produced by Certain Human SeraBrit. J. Exper. Path., 35
E. Henocq (1958)
Psoriasis and Dermatitis Originating in Sensitization to MouldsConcours méd., 80
A. Lorincz (1958)
OBSERVATIONS ON THE PROBLEM OF PATHOGENESIS IN PSORIASISAnnals of the New York Academy of Sciences, 73
L. T. Rosenberg (1958)
Passive Cutaneous AnaphylaxisRev. Allergy, 12
Z. Óváry (1958)
Immediate reactions in the skin of experimental animals provoked by antibody-antigen interaction.Progress in allergy, 5
R. Mackenna, Eric Cohen (1954)
Aids to dermatology
Abstract As in certain other diseases of unknown etiology, the possibility suggests itself that immunologic mechanisms may be involved in the pathogenesis of psoriasis. If this disease were to depend upon an autoimmune or allergic process, it is reasonable to expect that antihuman skin antibodies might be present in the sera of patients with psoriasis. To test for the presence of such antibodies, a specific immunologic procedure, the passive cutaneous anaphylactic (PCA) reaction, was used. This procedure has been shown to be a highly sensitive method for detecting known antigen-antibody interactions.1,2 Materials and Methods Specimens.— Sera were obtained from psoriatic patients and controls under sterile conditions. Punch biopsy specimens were taken under local anesthesia from active psoriatic plaques and from apparently uninvolved skin adjacent to them. Skin specimens and sera from subjects free of psoriasis were obtained from routine surgical cases and from patients with atopic dermatitis. All specimens were References 1. Ovary, A.: Immediate Reactions in the Skin of Experimental Animals Provoked by Antibody-Antigen Interaction , Prog. Allergy 5:459, 1958. 2. Rosenberg, L. T.: Passive Cutaneous Anaphylaxis , Rev. Allergy 12:710-716, 1958. 3. Lorincz, A. L.: Observations on the Problem of Pathogenesis in Psoriasis , Ann. New York Acad. Sc. 73:1000-1003, 1958.Crossref 4. Lovell, R. R. H.; Pryce, D. M., and Boake, W. C.: The Necrotic Lesions in Guinea-Pig Skin Produced by Certain Human Sera , Brit. J. Exper. Path. 35:345-350, 1954. 5. Henocq, E., and Guibert, L.: Psoriasis and Dermatitis Originating in Sensitization to Moulds , Concours méd. 80:4081-4088, 1958. 6. Benedek, T.: Rheumatoid Arthritis and Psoriasis Vulgaris , Ann Arbor, Mich., Edwards Brothers, Inc., 1955. 7. MacKenna, R. M. B.: Aids to Dermatology , Ed. 3, London, Bailliere, Tindall & Cox, 1946, p. 217.
Archives of Dermatology – American Medical Association
Published: Nov 1, 1960
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