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Unusual Eruptions Associated with Internal Malignant Disease

Unusual Eruptions Associated with Internal Malignant Disease Abstract Many years ago, Erasmus Wilson asserted that "cutaneous medicine is a branch of general medicine of no insignificant importance," and there is no doubt that we dermatologists are pervaded by a particular pleasure when we recognize that the patient's cutaneous lesions are the signs pointing to some general disease, such as diabetes or tuberculosis. Especially we are alert to the possibility that an unexplained pruritus or that a trivial, nonirritating but persistent rash may be the first sign of malignancy, such as mycosis fungoides, Hodgkin's disease, or carcinoma of the colon. For example, in May of this year a man was referred to us with an extensive vesicobullous eruption, somewhat resembling Duhring's disease but mainly localized to the arm, thighs, and upper back, areas which had been in contact with sacks containing cement. Histological examination of an intact bulla showed that the rash was eczematous References 1. Hamilton Montgomery and R. K. Winkelmann have published their article: Smooth-Muscle Tumors of the Skin , A. M. A. Arch. Dermat. 79:32-41, 1959.Crossref 2. J. Levack and A. Dick ( Cutaneous Leiomyosarcoma with Lymphatic Spread: A Report of 2 Cases , Glasgow M. J. 36:337-342, 1955). 3. Montgomery, H.: Leiomyomata, to be published. 4. Stout, A. P.: Leiomyomata , Am. J. Cancer 29:435, 1937.Crossref 5. Devic, A., and Gallavardin, L.: Leiomyoma Maligne , Rev. chir. 24:282, 1901. 6. Bartkowiak, Z.: Ein Fall von Sarcoma Leiomyoblasticum der Haut , Zentralbl. allg. Path. 65:179, 1936. 7. Ritchie, A. C.: Carcinoid Tumors , Am. J. M. Sc. 232:311, 1956.Crossref 8. Mattingly, T. W.: The Functioning Carcinoid Tumour—a New Clinical Entity: Review of the Clinical Features of the Non-Functioning and Functioning Carcinoid, Including a Review of 38 Cases from the Literature , M. Ann. District of Columbia 25:304 and 355, 1956. 9. Shafer, J. C., in discussion on Kierland, R. R.; Sauer, W. G., and Dearing, W. H.: The Cutaneous Manifestations of the Functioning Carcinoid , A. M. A. Arch. Dermat. 77:86, 1958.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Unusual Eruptions Associated with Internal Malignant Disease

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1959.01560230050009
Publisher site
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Abstract

Abstract Many years ago, Erasmus Wilson asserted that "cutaneous medicine is a branch of general medicine of no insignificant importance," and there is no doubt that we dermatologists are pervaded by a particular pleasure when we recognize that the patient's cutaneous lesions are the signs pointing to some general disease, such as diabetes or tuberculosis. Especially we are alert to the possibility that an unexplained pruritus or that a trivial, nonirritating but persistent rash may be the first sign of malignancy, such as mycosis fungoides, Hodgkin's disease, or carcinoma of the colon. For example, in May of this year a man was referred to us with an extensive vesicobullous eruption, somewhat resembling Duhring's disease but mainly localized to the arm, thighs, and upper back, areas which had been in contact with sacks containing cement. Histological examination of an intact bulla showed that the rash was eczematous References 1. Hamilton Montgomery and R. K. Winkelmann have published their article: Smooth-Muscle Tumors of the Skin , A. M. A. Arch. Dermat. 79:32-41, 1959.Crossref 2. J. Levack and A. Dick ( Cutaneous Leiomyosarcoma with Lymphatic Spread: A Report of 2 Cases , Glasgow M. J. 36:337-342, 1955). 3. Montgomery, H.: Leiomyomata, to be published. 4. Stout, A. P.: Leiomyomata , Am. J. Cancer 29:435, 1937.Crossref 5. Devic, A., and Gallavardin, L.: Leiomyoma Maligne , Rev. chir. 24:282, 1901. 6. Bartkowiak, Z.: Ein Fall von Sarcoma Leiomyoblasticum der Haut , Zentralbl. allg. Path. 65:179, 1936. 7. Ritchie, A. C.: Carcinoid Tumors , Am. J. M. Sc. 232:311, 1956.Crossref 8. Mattingly, T. W.: The Functioning Carcinoid Tumour—a New Clinical Entity: Review of the Clinical Features of the Non-Functioning and Functioning Carcinoid, Including a Review of 38 Cases from the Literature , M. Ann. District of Columbia 25:304 and 355, 1956. 9. Shafer, J. C., in discussion on Kierland, R. R.; Sauer, W. G., and Dearing, W. H.: The Cutaneous Manifestations of the Functioning Carcinoid , A. M. A. Arch. Dermat. 77:86, 1958.Crossref

Journal

A.M.A. Archives of Dermatology – American Medical Association

Published: Nov 1, 1959

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