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Treatment of Acute Parapsoriasis with Corticotropin (ACTH): Report of a Case

Treatment of Acute Parapsoriasis with Corticotropin (ACTH): Report of a Case Abstract Acute guttate parapsoriasis, or pityriasis lichenoides et varioliformis acuta of Mucha-Habermann, is an entity better known for the length of its name than for the importance of any clinical information concerning it. Our studies in the past several years, and recently those of Piérard and Van Steenbergen,1 have led us to the conclusion that microscopic hemorrhage is the typical histologic finding in this entity and that the hemorrhage occurs on the basis of intense inflammation of capillaries. Szymanski2 recently discussed a large series of these cases on the basis of allergic angiitis as the etiologic factor. The variable clinical lesions could be explained on such a basis. While this progress in the basic understanding of some of the clinical and histopathologic features of the disease was being made, no progress in treatment has been recorded for many years. Canizares3 reported success with References 1. Piérard, J., and Van Steenbergen, E. P.: A propos du Parapsoriasis varioliforme et de son histologie , Ann. dermat. et syph. 84:630-646 ( (Nov.) -Dec.) 1957. 2. Szymanski, F. J.: Pityriasis Lichenoides et Varioliformis Acuta , A. M. A. Arch. Dermat. 79:7-16 ( (Jan.) ) 1959.Crossref 3. Canizares, O.: Parapsoriasis: Its Treatment with Calciferol: Review of 18 Cases , A. M. A. Arch. Dermat. & Syph. 65:675-684 ( (June) ) 1952. 4. Rupp, V. E., and Blaese, C.: Pityriasis Lichenoides et Varioliformis Acuta Mucha-Habermann , Ztschr. Haut- u. Geschl. Kr. 23:238-241 ( (Oct. 15) ) 1957. 5. Degos, R.; Delort, J.; Civatte, J., and Kaufmann, P.: Parapsoriasis en gouttes avec poussée aiguë grave et hautement fébrile, abstracted , Bull. Soc. franç. dermat. et syph. 63:323-324 ( (May 3) ) 1956. 6. Ingram, J. T.: Pityriasis Lichenoides and Parapsoriasis , Brit. J. Dermat. 65:293-299 ( (Sept.) ) 1953. 7. Winkelmann, R. K.: Clinical and Pathologic Findings in the Skin in Anaphylactoid Purpura (Allergic Angiitis) , Proc. Staff Meet. Mayo Clin. 33:277-288 ( (May 28) ) 1958. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

Treatment of Acute Parapsoriasis with Corticotropin (ACTH): Report of a Case

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References (9)

Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1959.01560170010002
Publisher site
See Article on Publisher Site

Abstract

Abstract Acute guttate parapsoriasis, or pityriasis lichenoides et varioliformis acuta of Mucha-Habermann, is an entity better known for the length of its name than for the importance of any clinical information concerning it. Our studies in the past several years, and recently those of Piérard and Van Steenbergen,1 have led us to the conclusion that microscopic hemorrhage is the typical histologic finding in this entity and that the hemorrhage occurs on the basis of intense inflammation of capillaries. Szymanski2 recently discussed a large series of these cases on the basis of allergic angiitis as the etiologic factor. The variable clinical lesions could be explained on such a basis. While this progress in the basic understanding of some of the clinical and histopathologic features of the disease was being made, no progress in treatment has been recorded for many years. Canizares3 reported success with References 1. Piérard, J., and Van Steenbergen, E. P.: A propos du Parapsoriasis varioliforme et de son histologie , Ann. dermat. et syph. 84:630-646 ( (Nov.) -Dec.) 1957. 2. Szymanski, F. J.: Pityriasis Lichenoides et Varioliformis Acuta , A. M. A. Arch. Dermat. 79:7-16 ( (Jan.) ) 1959.Crossref 3. Canizares, O.: Parapsoriasis: Its Treatment with Calciferol: Review of 18 Cases , A. M. A. Arch. Dermat. & Syph. 65:675-684 ( (June) ) 1952. 4. Rupp, V. E., and Blaese, C.: Pityriasis Lichenoides et Varioliformis Acuta Mucha-Habermann , Ztschr. Haut- u. Geschl. Kr. 23:238-241 ( (Oct. 15) ) 1957. 5. Degos, R.; Delort, J.; Civatte, J., and Kaufmann, P.: Parapsoriasis en gouttes avec poussée aiguë grave et hautement fébrile, abstracted , Bull. Soc. franç. dermat. et syph. 63:323-324 ( (May 3) ) 1956. 6. Ingram, J. T.: Pityriasis Lichenoides and Parapsoriasis , Brit. J. Dermat. 65:293-299 ( (Sept.) ) 1953. 7. Winkelmann, R. K.: Clinical and Pathologic Findings in the Skin in Anaphylactoid Purpura (Allergic Angiitis) , Proc. Staff Meet. Mayo Clin. 33:277-288 ( (May 28) ) 1958.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: May 1, 1959

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