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A Clinical Application of a Hydrophilic Ointment Base: A Balanced Emulsion System

A Clinical Application of a Hydrophilic Ointment Base: A Balanced Emulsion System Abstract The increasing incidence of dermatitis of the hands has been a matter of concern to the dermatologist for some time. The literature* indicates that the so-called "housewives' eczema" is basically an external irritant dermatitis resulting from the contact with the agents used in the course of housework. Some have suggested that the synthetic detergents may be the etiologic factor.† However, many other known irritants may also be of contributory importance, and these are ammonia water, bleaches, phosphates, abrasive powders, organic solvent of waxes, and polishes, as well as the thermal changes encountered during normal activity. All of these agents contribute to the production of dermatitis in varying degrees in different patients. Similar eruptions may also be seen in persons engaged in occupations involving "wet work," and the problems encountered in the management of this type of eczematoid reaction are extremely complex. In References 1. References 1 and 2. 2. References 3 and 4. 3. Trade-mark of E. Fougera Co., New York. 4. Hodgsen, G.: Use of Household Detergents and Their Dangers , Practitioner , 170:166, 1953. 5. Gaul, L. E.: Dermatitis Venenata, Current Therapy (1954) , Philadelphia, W. B. Saunders Company, 1954, p. 597. 6. Emery, B. E., and Edward, L. D.: The Pharmacology of Soap; Irritant Action of Soaps on the Human Skin , J. Am. Pharm. A. 29:254, 1940.Crossref 7. Brunner, M. J.: Dermatitis of the Hands Due to Household Cleaners , J. A. M. A. 154:894, 1954.Crossref 8. Sulzberger, M. B., and Baer, R. L.: Unusual or Abnormal Effect of Soap on the "Normal" Skin, in Medical Uses of Soap , Philadelphia, J. B. Lippincott Company, 1946, p. 51. 9. Goodman, H.: The Skin Considered as an Emulsion , Am. Prof. Pharm. 20:956, 1954. 10. Halpern, A.: An Evaluation of Polysorb , Am. Prof. Pharm. 16:340, 1950. 11. Perrin, S. R.: Clinical Saftey of Polysorb , Postgraduate Med. 8:485, 1950. 12. Perrin, S. R., and Halpern, A.: A Comparative Study of the Use of Hydrophilic Absorption Ointment Bases , J. Invest. Dermat. 16:7, 1951. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

A Clinical Application of a Hydrophilic Ointment Base: A Balanced Emulsion System

A.M.A. Archives of Dermatology , Volume 71 (6) – Jun 1, 1955

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References (10)

Publisher
American Medical Association
Copyright
Copyright © 1955 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1955.01540300010003
Publisher site
See Article on Publisher Site

Abstract

Abstract The increasing incidence of dermatitis of the hands has been a matter of concern to the dermatologist for some time. The literature* indicates that the so-called "housewives' eczema" is basically an external irritant dermatitis resulting from the contact with the agents used in the course of housework. Some have suggested that the synthetic detergents may be the etiologic factor.† However, many other known irritants may also be of contributory importance, and these are ammonia water, bleaches, phosphates, abrasive powders, organic solvent of waxes, and polishes, as well as the thermal changes encountered during normal activity. All of these agents contribute to the production of dermatitis in varying degrees in different patients. Similar eruptions may also be seen in persons engaged in occupations involving "wet work," and the problems encountered in the management of this type of eczematoid reaction are extremely complex. In References 1. References 1 and 2. 2. References 3 and 4. 3. Trade-mark of E. Fougera Co., New York. 4. Hodgsen, G.: Use of Household Detergents and Their Dangers , Practitioner , 170:166, 1953. 5. Gaul, L. E.: Dermatitis Venenata, Current Therapy (1954) , Philadelphia, W. B. Saunders Company, 1954, p. 597. 6. Emery, B. E., and Edward, L. D.: The Pharmacology of Soap; Irritant Action of Soaps on the Human Skin , J. Am. Pharm. A. 29:254, 1940.Crossref 7. Brunner, M. J.: Dermatitis of the Hands Due to Household Cleaners , J. A. M. A. 154:894, 1954.Crossref 8. Sulzberger, M. B., and Baer, R. L.: Unusual or Abnormal Effect of Soap on the "Normal" Skin, in Medical Uses of Soap , Philadelphia, J. B. Lippincott Company, 1946, p. 51. 9. Goodman, H.: The Skin Considered as an Emulsion , Am. Prof. Pharm. 20:956, 1954. 10. Halpern, A.: An Evaluation of Polysorb , Am. Prof. Pharm. 16:340, 1950. 11. Perrin, S. R.: Clinical Saftey of Polysorb , Postgraduate Med. 8:485, 1950. 12. Perrin, S. R., and Halpern, A.: A Comparative Study of the Use of Hydrophilic Absorption Ointment Bases , J. Invest. Dermat. 16:7, 1951.

Journal

A.M.A. Archives of DermatologyAmerican Medical Association

Published: Jun 1, 1955

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