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BRONX DERMATOLOGICAL SOCIETY

BRONX DERMATOLOGICAL SOCIETY This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Clinical Evaluation of Tetracycline in Pustular Dermatoses. Presented by Dr. Charles R. Rein. A series of 106 patients with pustular dermatoses were treated with orally administered tetracycline. Of this group 90 patients were maintained on therapy of 1 gm. per day in four divided doses over a period of four weeks. Tetracycline was of definite value in that 42.2% had a marked improvement, 44.4% had a moderate improvement, and 13.3% showed a slight improvement. Adverse reactions appeared to be less frequent and less severe than with previously employed broad-spectrum antibiotics, and consisted of nausea, vomiting, cramps, flatus, diarrhea, anogenital pruritus, hairy tongue, stomatitis, and burning sensation in the throat. Tetracycline serum concentrations determined at varying intervals following completion of therapy gave measurable evidence of a cumulative effect. Preliminary investigations with a new Monilia complement-fixation test seem to indicate that: Tetracycline taken in doses of 1 gm. per day http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology American Medical Association

BRONX DERMATOLOGICAL SOCIETY

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Publisher
American Medical Association
Copyright
Copyright © 1955 American Medical Association. All Rights Reserved.
ISSN
0096-5359
DOI
10.1001/archderm.1955.01540290088029
Publisher site
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Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Clinical Evaluation of Tetracycline in Pustular Dermatoses. Presented by Dr. Charles R. Rein. A series of 106 patients with pustular dermatoses were treated with orally administered tetracycline. Of this group 90 patients were maintained on therapy of 1 gm. per day in four divided doses over a period of four weeks. Tetracycline was of definite value in that 42.2% had a marked improvement, 44.4% had a moderate improvement, and 13.3% showed a slight improvement. Adverse reactions appeared to be less frequent and less severe than with previously employed broad-spectrum antibiotics, and consisted of nausea, vomiting, cramps, flatus, diarrhea, anogenital pruritus, hairy tongue, stomatitis, and burning sensation in the throat. Tetracycline serum concentrations determined at varying intervals following completion of therapy gave measurable evidence of a cumulative effect. Preliminary investigations with a new Monilia complement-fixation test seem to indicate that: Tetracycline taken in doses of 1 gm. per day

Journal

A.M.A. Archives of Dermatology – American Medical Association

Published: May 1, 1955

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