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H. Robinson, R. Robinson (1954)
Treatment of dermatoses with local application of hydrocortisone acetate.Journal of the American Medical Association, 155 14
M. Sulzberger, V. Witten, C. Smith (1953)
Hydrocortisone (compound F) acetate ointment in dermatological therapy.Journal of the American Medical Association, 151 6
B. Heilson , A. Kristjansen (1954)
Hydrocortisone in Therapy of Cutaneous DiseaseA. M. A. Arch. Dermat. & Syph., 70
H. M. Robinson (1954)
Treatment of Dermatoses with Local Application of Hydrocortisone AcetateJ. A. M. A., 155
M. B. Sulzberger , V. H. Witten (1953)
Hydrocortisone (Compound F) Free Alcohol Ointment, CorrespondenceJ. A. M. A., 152
L. Frank , C. Stritzler (1955)
Hydrocortisone (Compound F) Free Alcohol and Hydrocortisone Acetate for Topical UseA. M. A. Arch. Dermat., 71
M. Sulzberger, V. Witten, C. Smith (1953)
Hydrocortisone (compound F) free alcohol ointment.Journal of the American Medical Association, 152 15
M. B. Sulzberger (1953)
Hydrocortisone (Compound F) Acetate Ointment in Dermatological TherapyJ. A. M. A., 151
Abstract Hydrocortisone has now been established as an effective medication for topical use in many dermatologic conditions.* Most investigators have reported on the value of a 1% concentration of hydrocortisone acetate and have stated that concentrations below 1% were of no value.† It has recently been shown,‡ however, that the free alcohol of hydrocortisone is more effective topically than the hydrocortisone acetate. Accordingly, an ointment containing a concentration of a 0.5% hydrocortisone free alcohol was clinically evaluated and compared with the same ointment in a 1% concentration. Our results showed that a 0.5% hydrocortisone free alcohol ointment is a useful and effective medication topically. METHODS AND MATERIALS Two hundred eighty-two patients were treated with two ointments containing a concentration of 0.5% hydrocortisone free alcohol and 1% hydrocortisone free alcohol. Wherever possible, contralateral areas were treated with each ointment for comparative evaluation. References 1. References 1, 2, and 3. 2. References 2 and 4. 3. References 3 and 5. 4. Sulzberger, M. B., and Witten, V. H.: Hydrocortisone (Compound F) Acetate Ointment in Dermatological Therapy , J. A. M. A. 151:468, ( (Feb. 7) ) 1953. 5. Robinson, H. M., Jr., and Robinson, R. C. V.: Treatment of Dermatoses with Local Application of Hydrocortisone Acetate , J. A. M. A. 155:1213 ( (July 31) ) 1954.Crossref 6. Frank, L.; Stritzler, C., and Kaufman, J.: Hydrocortisone (Compound F) Free Alcohol and Hydrocortisone Acetate for Topical Use , A. M. A. Arch. Dermat. 71:117 ( (Jan.) ) 1955.Crossref 7. Heilson, B.; Kristjansen, A., and Reymann, F.: Hydrocortisone in Therapy of Cutaneous Disease , A. M. A. Arch. Dermat. & Syph. 70:360 ( (Sept.) ) 1954. 8. Sulzberger, M. B.; Witten, V. H., and Smith, C. C.: Hydrocortisone (Compound F) Free Alcohol Ointment, Correspondence , J. A. M. A. 152:1456 ( (Aug. 8) ) 1953.
A.M.A. Archives of Dermatology – American Medical Association
Published: May 1, 1955
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