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USE OF ORAL PROCAINE IN CONTROL OF PRURITUS

USE OF ORAL PROCAINE IN CONTROL OF PRURITUS Abstract THE EXPERIENCE of my colleagues and me with the use of intravenous procaine for the control of pruritus has been recorded.1 The following report covers the results of the treatment of pruritus with procaine hydrochloride administered orally. One hundred forty-five patients, representing 23 pruritic dermatoses, were studied. Seventy-eight patients had received no previous medication, and the remaining 67 had received no relief from varied types of therapy previously administered. In the latter group were included 20 patients previously treated with intravenous injections of procaine, without relief. These will be commented upon later. For the sake of convenience, we classified these patients on a neurogenic and miscellaneous basis. In 1950, our attention was called to the use of oral procaine by Roka and Lajtha.2 They prescribed procaine in aqueous solution by mouth to abolish pylorospasm. In the same year, Schapiro and Sadove3 reported a patient References 1. Tedral formula: theophylline 2 grains (0.12 gm.), ephedrine ⅜ grains (0.022 gm.), and phenobarbital ⅛ grains (0.007 gm.). 2. References 4 and 5. 3. Beinhauer, L. G.; Thomas, G. J., and Perrin, S. R.: Intravenous Use of Procaine Hydrochloride in Control of Pruritus , A. M. A. Arch. Dermat. & Syph. 65:39 ( (Jan.) ) 1952. 4. Roka, G., and Lajtha, L. G.: Abolition of Pyloric Spasm by Oral Administered Procaine Solutions , Brit. M. J. 1:1174 ( (May 20) ) 1950. 5. Schapiro, M. M., and Sadove, M. S.: Oral Procaine Hydrochloride Therapy in Asthma ; Ann. Allergy 8:85, ( (Jan.) -Feb.) 1950. 6. Luddecke, H.: Oral Administration of Procaine with Ascorbic Acid, with Special Reference to Therapy of Pruritis , A. M. A. Arch. Dermat. Syph. 64:9 ( (July) ) 1951. 7. Markow, H.; Bloom, S., and Kleinman, A. I.: Comparative Effectiveness of Oral Procaine and Tedral in Allergic Conditions , Ann. Allergy , 10:58 ( (Jan.) -Feb.) 1952. 8. Ellis, M. E.: Oral Use of Procaine , J. Michigan M. Soc. 51:490 ( (April) ) 1952. 9. Balfour, D. C., Jr., and Wharton, G. K.: Use of Procaine Hydrochloride by Mouth for Gastrointestinal Disorders , Gastroenterology 22:257 ( (Oct.) ) 1952. 10. Cushny, A. R.: Pharmacology and Therapeutics , Ed. 13, Philadelphia, Lea & Febiger, 1947, p. 412. 11. State, D., and Wangensteen, O. H.: Procaine Intravenously in the Treatment of Delayed Serum Sickness , J. A. M. A. 130:990 ( (April 13) ) 1946. 12. Criep, L. H., and Ribeiro, C. de C.: Allergy to Procaine Hydrochloride with 3 Fatalities , J. A. M. A. 151:1185 ( (April 4) ) 1953. 13. Davis, H. S., and Bryce-Smith, R.: Allergy and Procaine Hydrochloride, Correspondence , J. A. M. A. 152:477 ( (May 30) ) 1953. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

USE OF ORAL PROCAINE IN CONTROL OF PRURITUS

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References (16)

Publisher
American Medical Association
Copyright
Copyright © 1954 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1954.01540140056004
Publisher site
See Article on Publisher Site

Abstract

Abstract THE EXPERIENCE of my colleagues and me with the use of intravenous procaine for the control of pruritus has been recorded.1 The following report covers the results of the treatment of pruritus with procaine hydrochloride administered orally. One hundred forty-five patients, representing 23 pruritic dermatoses, were studied. Seventy-eight patients had received no previous medication, and the remaining 67 had received no relief from varied types of therapy previously administered. In the latter group were included 20 patients previously treated with intravenous injections of procaine, without relief. These will be commented upon later. For the sake of convenience, we classified these patients on a neurogenic and miscellaneous basis. In 1950, our attention was called to the use of oral procaine by Roka and Lajtha.2 They prescribed procaine in aqueous solution by mouth to abolish pylorospasm. In the same year, Schapiro and Sadove3 reported a patient References 1. Tedral formula: theophylline 2 grains (0.12 gm.), ephedrine ⅜ grains (0.022 gm.), and phenobarbital ⅛ grains (0.007 gm.). 2. References 4 and 5. 3. Beinhauer, L. G.; Thomas, G. J., and Perrin, S. R.: Intravenous Use of Procaine Hydrochloride in Control of Pruritus , A. M. A. Arch. Dermat. & Syph. 65:39 ( (Jan.) ) 1952. 4. Roka, G., and Lajtha, L. G.: Abolition of Pyloric Spasm by Oral Administered Procaine Solutions , Brit. M. J. 1:1174 ( (May 20) ) 1950. 5. Schapiro, M. M., and Sadove, M. S.: Oral Procaine Hydrochloride Therapy in Asthma ; Ann. Allergy 8:85, ( (Jan.) -Feb.) 1950. 6. Luddecke, H.: Oral Administration of Procaine with Ascorbic Acid, with Special Reference to Therapy of Pruritis , A. M. A. Arch. Dermat. Syph. 64:9 ( (July) ) 1951. 7. Markow, H.; Bloom, S., and Kleinman, A. I.: Comparative Effectiveness of Oral Procaine and Tedral in Allergic Conditions , Ann. Allergy , 10:58 ( (Jan.) -Feb.) 1952. 8. Ellis, M. E.: Oral Use of Procaine , J. Michigan M. Soc. 51:490 ( (April) ) 1952. 9. Balfour, D. C., Jr., and Wharton, G. K.: Use of Procaine Hydrochloride by Mouth for Gastrointestinal Disorders , Gastroenterology 22:257 ( (Oct.) ) 1952. 10. Cushny, A. R.: Pharmacology and Therapeutics , Ed. 13, Philadelphia, Lea & Febiger, 1947, p. 412. 11. State, D., and Wangensteen, O. H.: Procaine Intravenously in the Treatment of Delayed Serum Sickness , J. A. M. A. 130:990 ( (April 13) ) 1946. 12. Criep, L. H., and Ribeiro, C. de C.: Allergy to Procaine Hydrochloride with 3 Fatalities , J. A. M. A. 151:1185 ( (April 4) ) 1953. 13. Davis, H. S., and Bryce-Smith, R.: Allergy and Procaine Hydrochloride, Correspondence , J. A. M. A. 152:477 ( (May 30) ) 1953.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Feb 1, 1954

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