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SQUAMOUS CELL CARCINOMA OF THE VULVA SECONDARY TO GRANULOMA INGUINALE

SQUAMOUS CELL CARCINOMA OF THE VULVA SECONDARY TO GRANULOMA INGUINALE Abstract THE CASE to be described is the first in the literature in which the development of carcinoma of the vulva secondary to granuloma inguinale is without doubt. There are in the literature, however, case reports of squamous cell carcinoma of the genitalia that developed at sites previously involved by granuloma inguinale, but none in which this sequence of events can go unquestioned with regard to the vulva itself. REPORT OF A CASE W. G. (No. 38-901), a 16-year-old Negro girl, was admitted to the clinic on Oct. 14, 1938, because of multiple lesions of the vulva of approximately six months' duration. The lesions were granulomatous, beefy red, and covered with a serosanguineous exudate; they involved the fourchette of the vagina, a part of the right vaginal wall, the right labium minus and labium majus, the right genitocrural fold, and in great part the right inguinal region. There were References 1. Alexander, L. J., and Schoch, A. G.: Granuloma Inguinale: The Successful Use of Giemsa Stain to Demonstrate Typical Pathologic Findings , Am. J. Syph. 24:180-183 ( (March) ) 1940. 2. Kern, A. B.: Squamous Cell Carcinoma Simulating Granuloma Inguinale , Arch. Dermat. & Syph. 62:515-525 ( (Oct.) ) 1950. 3. Cardwell, E. S., Jr., and Pund, E. R.: Malignancies Related to Venereal Disease: Development of Carcinoma Secondary to Venereal Lymphogranuloma and Granuloma, and Carcinoma , J. M. A. Georgia 29:60-62 ( (Feb.) ) 1940. 4. Pund, E. R.; Greenblatt, R. B., and Huie, G. B.: The Role of the Biopsy in Diagnosis of Venereal Diseases: Histologic Differentiation of Venereal Granuloma and Lymphogranuloma and Chancroid , Am. J. Syph. 22:495-502 ( (July) ) 1938. 5. Lynch, K. M.: Granuloma Inguinale , J. A. M. A. 77:925 ( (Sept. 17) ) 1921. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

SQUAMOUS CELL CARCINOMA OF THE VULVA SECONDARY TO GRANULOMA INGUINALE

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1953 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1953.01540040053008
Publisher site
See Article on Publisher Site

Abstract

Abstract THE CASE to be described is the first in the literature in which the development of carcinoma of the vulva secondary to granuloma inguinale is without doubt. There are in the literature, however, case reports of squamous cell carcinoma of the genitalia that developed at sites previously involved by granuloma inguinale, but none in which this sequence of events can go unquestioned with regard to the vulva itself. REPORT OF A CASE W. G. (No. 38-901), a 16-year-old Negro girl, was admitted to the clinic on Oct. 14, 1938, because of multiple lesions of the vulva of approximately six months' duration. The lesions were granulomatous, beefy red, and covered with a serosanguineous exudate; they involved the fourchette of the vagina, a part of the right vaginal wall, the right labium minus and labium majus, the right genitocrural fold, and in great part the right inguinal region. There were References 1. Alexander, L. J., and Schoch, A. G.: Granuloma Inguinale: The Successful Use of Giemsa Stain to Demonstrate Typical Pathologic Findings , Am. J. Syph. 24:180-183 ( (March) ) 1940. 2. Kern, A. B.: Squamous Cell Carcinoma Simulating Granuloma Inguinale , Arch. Dermat. & Syph. 62:515-525 ( (Oct.) ) 1950. 3. Cardwell, E. S., Jr., and Pund, E. R.: Malignancies Related to Venereal Disease: Development of Carcinoma Secondary to Venereal Lymphogranuloma and Granuloma, and Carcinoma , J. M. A. Georgia 29:60-62 ( (Feb.) ) 1940. 4. Pund, E. R.; Greenblatt, R. B., and Huie, G. B.: The Role of the Biopsy in Diagnosis of Venereal Diseases: Histologic Differentiation of Venereal Granuloma and Lymphogranuloma and Chancroid , Am. J. Syph. 22:495-502 ( (July) ) 1938. 5. Lynch, K. M.: Granuloma Inguinale , J. A. M. A. 77:925 ( (Sept. 17) ) 1921.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Apr 1, 1953

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