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STREPTOMYCIN THERAPY OF ERYTHEMA INDURATUM

STREPTOMYCIN THERAPY OF ERYTHEMA INDURATUM Abstract Since streptomycin was first isolated from Streptomyces griseus, in September 1943, reports have appeared in the medical literature concerning its efficacy in treating various diseases of the skin.1 Those conditions which have been reported as amenable to streptomycin therapy include lupus vulgaris, scrofuloderma, tuberculosis miliaris disseminata faciei, tuberculous ulcers of the tongue, tuberculosis verrucosa cutis, actinomycosis, tularemia, chancroid, granuloma inguinale and various dermatoses due to Pseudomonas aeruginosa (Bacillus pyocyaneus).2 A careful search of the literature fails to reveal any reports on the treatment of erythema induratum with this antibiotic, and therefore two cases from the dermatology clinic at the Vanderbilt University Hospital are being recorded. REPORT OF CASES Case 1.— E. M., a 36 year old white housewife, was first seen in October 1945 at the Vanderbilt University clinic. The "glands in her neck" had begun enlarging eight months earlier, and a sudden acute swelling had appeared the preceding References 1. Waksman, S. A.: Streptomycin: Nature and Practical Applications , Baltimore, Williams & Wilkins Company, 1949. 2. Delamater, E. D., in Waksman,1 pp. 520-523. 3. O'Leary, P. A.; Ceder, E. T.; Hinshaw, H. C., and Feldman, W. H.: Treatment of Various Types of Cutaneous Tuberculosis with Promizole and Streptomycin: Preliminary Report , Arch. Dermat. & Syph. 55:222-232 ( (Feb.) ) 1947 4. Combes, F. C.; Canizares, O.; Shatin, H., and Kaufman, C.: Streptomycin in Dermatology: Its Value and Limitations , New York J. Med. 48:2024-2028, 1948. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

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References (4)

Publisher
American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1951.01570070052008
Publisher site
See Article on Publisher Site

Abstract

Abstract Since streptomycin was first isolated from Streptomyces griseus, in September 1943, reports have appeared in the medical literature concerning its efficacy in treating various diseases of the skin.1 Those conditions which have been reported as amenable to streptomycin therapy include lupus vulgaris, scrofuloderma, tuberculosis miliaris disseminata faciei, tuberculous ulcers of the tongue, tuberculosis verrucosa cutis, actinomycosis, tularemia, chancroid, granuloma inguinale and various dermatoses due to Pseudomonas aeruginosa (Bacillus pyocyaneus).2 A careful search of the literature fails to reveal any reports on the treatment of erythema induratum with this antibiotic, and therefore two cases from the dermatology clinic at the Vanderbilt University Hospital are being recorded. REPORT OF CASES Case 1.— E. M., a 36 year old white housewife, was first seen in October 1945 at the Vanderbilt University clinic. The "glands in her neck" had begun enlarging eight months earlier, and a sudden acute swelling had appeared the preceding References 1. Waksman, S. A.: Streptomycin: Nature and Practical Applications , Baltimore, Williams & Wilkins Company, 1949. 2. Delamater, E. D., in Waksman,1 pp. 520-523. 3. O'Leary, P. A.; Ceder, E. T.; Hinshaw, H. C., and Feldman, W. H.: Treatment of Various Types of Cutaneous Tuberculosis with Promizole and Streptomycin: Preliminary Report , Arch. Dermat. & Syph. 55:222-232 ( (Feb.) ) 1947 4. Combes, F. C.; Canizares, O.; Shatin, H., and Kaufman, C.: Streptomycin in Dermatology: Its Value and Limitations , New York J. Med. 48:2024-2028, 1948.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Jul 1, 1951

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