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TREATMENT OF CUTANEOUS BLASTOMAS AND OTHER DISEASES WITH NITROGEN MUSTARD

TREATMENT OF CUTANEOUS BLASTOMAS AND OTHER DISEASES WITH NITROGEN MUSTARD Abstract IT IS IMPORTANT that persons connected with all phases of medicine interest themselves in the study and application of new drugs and chemicals, particularly when allied diseases of the various specialties may be benefited by them. Nitrogen mustard is a relatively new chemical so far as its therapeutic and biologic actions in diseases, as first reported by Gilman and Philips,1 are concerned. An official statement of its merits was made by Rhoads.2 Both of these writers thoroughly discussed its chemistry and modes of action, and so further reference to this phase of the chemical will not be made. Though it is more than likely that numerous persons have treated cutaneous blastomas and other diseases with nitrogen mustard, there are only a few reports in the literature at this time. For that reason it was felt that the present report might be of interest. Henstell and Tober3 References 1. Gilman, A., and Philips, F. S.: The Biological Actions and Therapeutic Applications of the B-Chloroethyl Amines and Sulfides , Science 103:409-415, 1946.Crossref 2. Rhoads, C. P.: Nitrogen Mustards in the Treatment of Neoplastic Disease: Official Statement , J. A. M. A. 131:656-658 ( (June 22) ) 1946.Crossref 3. Henstell, H. H., and Tober, J. N.: Treatment of Mycosis Fungoides with Nitrogen Mustard , J. Invest. Dermat. 8:183-188, 1947. 4. Kierland, R. R.; Watkins, C. H., and Shullenberger, C. C.: The Use of Nitrogen Mustard in the Treatment of Mycosis Fungoides , J. Invest. Dermat. 9:195-203, 1947.Crossref 5. Philpott, O. S.; Woodburne, A. R., and Waldriff, G.: Nitrogen Mustard in the Treatment of Mycosis Fungoides , J. A. M. A. 135:631-633 ( (Nov. 8) ) 1947.Crossref 6. Osborne, E. D.; Jordan, J. W.; Hoak, F. C., and Pschierer, F. J.: Nitrogen Mustard Therapy in Cutaneous Blastomatous Disease , J. A. M. A. 135:1123-1128 ( (Dec. 27) ) 1947.Crossref 7. Henstell, H. H.; Tober, J. N., and Newman, B. A.: The Influence of Nitrogen Mustard on Mycosis Fungoides , Blood 2:574-578, 1947. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

TREATMENT OF CUTANEOUS BLASTOMAS AND OTHER DISEASES WITH NITROGEN MUSTARD

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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1949 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1949.01530020049008
Publisher site
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Abstract

Abstract IT IS IMPORTANT that persons connected with all phases of medicine interest themselves in the study and application of new drugs and chemicals, particularly when allied diseases of the various specialties may be benefited by them. Nitrogen mustard is a relatively new chemical so far as its therapeutic and biologic actions in diseases, as first reported by Gilman and Philips,1 are concerned. An official statement of its merits was made by Rhoads.2 Both of these writers thoroughly discussed its chemistry and modes of action, and so further reference to this phase of the chemical will not be made. Though it is more than likely that numerous persons have treated cutaneous blastomas and other diseases with nitrogen mustard, there are only a few reports in the literature at this time. For that reason it was felt that the present report might be of interest. Henstell and Tober3 References 1. Gilman, A., and Philips, F. S.: The Biological Actions and Therapeutic Applications of the B-Chloroethyl Amines and Sulfides , Science 103:409-415, 1946.Crossref 2. Rhoads, C. P.: Nitrogen Mustards in the Treatment of Neoplastic Disease: Official Statement , J. A. M. A. 131:656-658 ( (June 22) ) 1946.Crossref 3. Henstell, H. H., and Tober, J. N.: Treatment of Mycosis Fungoides with Nitrogen Mustard , J. Invest. Dermat. 8:183-188, 1947. 4. Kierland, R. R.; Watkins, C. H., and Shullenberger, C. C.: The Use of Nitrogen Mustard in the Treatment of Mycosis Fungoides , J. Invest. Dermat. 9:195-203, 1947.Crossref 5. Philpott, O. S.; Woodburne, A. R., and Waldriff, G.: Nitrogen Mustard in the Treatment of Mycosis Fungoides , J. A. M. A. 135:631-633 ( (Nov. 8) ) 1947.Crossref 6. Osborne, E. D.; Jordan, J. W.; Hoak, F. C., and Pschierer, F. J.: Nitrogen Mustard Therapy in Cutaneous Blastomatous Disease , J. A. M. A. 135:1123-1128 ( (Dec. 27) ) 1947.Crossref 7. Henstell, H. H.; Tober, J. N., and Newman, B. A.: The Influence of Nitrogen Mustard on Mycosis Fungoides , Blood 2:574-578, 1947.

Journal

Archives of Dermatology and Syphilology – American Medical Association

Published: Aug 1, 1949

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