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CONTACT ECZEMATOUS DERMATITIS AND PATCH TESTS: A Histologic Study

CONTACT ECZEMATOUS DERMATITIS AND PATCH TESTS: A Histologic Study Abstract IN A previous paper1 the histology of the eczematoid dermatoses was discussed. Mention was made of the histologic reactions in contact eczematous dermatitis. In this paper a further detailed study will be made. The observations in patch tests will also be considered. From the histologic standpoint, the term acute dermatitis is used to express an inflammatory reaction confined to the upper third of the cutis and characterized by congestion, edema and cellular infiltration. This infiltration is composed of round cells and wandering connective tissue cells. The term eczema microscopically refers to a dermoepidermic process, in which there is intraepidermic vesicular formation at some time. In addition to the changes in the cutis there are changes in the epidermis. These changes are (1) intercellular edema, (2) spongiosis and (3) vesicular formation. The horny zone shows patchy areas of parakeratosis. The term contact dermatitis is a misnomer, since there are histologic References 1. Sachs, W.; Miller, C. S., and Gray, M.: Histopathology of the Eczematoid Dermatoses , Ann. Allergy 2:289 ( (July) -Aug.) 1944. 2. Sulzberger, M. B., and Wolf, J.: Dermatologic Therapy in General Practice , Chicago, The Year Book Publishers, Inc., 1940, p. 115. 3. Sulzberger, M. B.: Dermatologic Allergy , Springfield, Ill., Charles C Thomas, Publisher, 1940, p. 93. 4. Macleod, J. M. H., and Muende, I.: Practical Handbook of Pathology of the Skin , New York, Paul B. Hoeber, Inc., 1940, p. 83. 5. Macleod and Muende,3 p. 6. Footnote 2b p. 175. 7. Sachs, W.; Miller, C. S., and Gray M.: Neurodermatitic Reaction , Arch. Dermat. & Syph. 54:397 ( (Oct.) ) 1946. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

CONTACT ECZEMATOUS DERMATITIS AND PATCH TESTS: A Histologic Study

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1947 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1947.01520110124016
Publisher site
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Abstract

Abstract IN A previous paper1 the histology of the eczematoid dermatoses was discussed. Mention was made of the histologic reactions in contact eczematous dermatitis. In this paper a further detailed study will be made. The observations in patch tests will also be considered. From the histologic standpoint, the term acute dermatitis is used to express an inflammatory reaction confined to the upper third of the cutis and characterized by congestion, edema and cellular infiltration. This infiltration is composed of round cells and wandering connective tissue cells. The term eczema microscopically refers to a dermoepidermic process, in which there is intraepidermic vesicular formation at some time. In addition to the changes in the cutis there are changes in the epidermis. These changes are (1) intercellular edema, (2) spongiosis and (3) vesicular formation. The horny zone shows patchy areas of parakeratosis. The term contact dermatitis is a misnomer, since there are histologic References 1. Sachs, W.; Miller, C. S., and Gray, M.: Histopathology of the Eczematoid Dermatoses , Ann. Allergy 2:289 ( (July) -Aug.) 1944. 2. Sulzberger, M. B., and Wolf, J.: Dermatologic Therapy in General Practice , Chicago, The Year Book Publishers, Inc., 1940, p. 115. 3. Sulzberger, M. B.: Dermatologic Allergy , Springfield, Ill., Charles C Thomas, Publisher, 1940, p. 93. 4. Macleod, J. M. H., and Muende, I.: Practical Handbook of Pathology of the Skin , New York, Paul B. Hoeber, Inc., 1940, p. 83. 5. Macleod and Muende,3 p. 6. Footnote 2b p. 175. 7. Sachs, W.; Miller, C. S., and Gray M.: Neurodermatitic Reaction , Arch. Dermat. & Syph. 54:397 ( (Oct.) ) 1946.

Journal

Archives of Dermatology and Syphilology – American Medical Association

Published: Nov 1, 1947

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