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TOPICAL USE OF PENICILLIN IN TREATMENT OF PYODERMA

TOPICAL USE OF PENICILLIN IN TREATMENT OF PYODERMA Abstract PRIMARY and secondary pyogenic infections of the skin make up a large proportion of dermatologic conditions in patients in the military services. In the hot and more tropical areas this group assumes increasing importance and comprises a constant problem. The amazing effectiveness of penicillin on some of the pyogenic organisms would warrant a trial in purulent infections of the skin in which the process could be subjected directly to penicillin. Penicillin has been incorporated into water-miscible bases in varying concentrations. Cohen and Pfaff1 used 1,666 units of penicillin per gram, with effectiveness, in impetigo contagiosa, carbuncles, herpes zoster with secondary impetigo and sycosis barbae. Johnson2 reported excellent results in the same type of cases using a concentration of 166 units per gram of ointment base. Vesicular and intertriginous fungous infections of the feet having secondary invasion by staphylococci and streptococci constitute a large group of conditions in patients References 1. Cohen, T. M., and Pfaff, R. O.: Penicillin in Dermatologic Therapy: Report of Results in One Hundred Cases , Arch. Dermat. & Syph. 51:172-177 ( (March) ) 1945. 2. Johnson, H. M.: Penicillin Ointment for Pyodermas, to be published. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

TOPICAL USE OF PENICILLIN IN TREATMENT OF PYODERMA

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References (1)

Publisher
American Medical Association
Copyright
Copyright © 1947 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1947.01520050032003
Publisher site
See Article on Publisher Site

Abstract

Abstract PRIMARY and secondary pyogenic infections of the skin make up a large proportion of dermatologic conditions in patients in the military services. In the hot and more tropical areas this group assumes increasing importance and comprises a constant problem. The amazing effectiveness of penicillin on some of the pyogenic organisms would warrant a trial in purulent infections of the skin in which the process could be subjected directly to penicillin. Penicillin has been incorporated into water-miscible bases in varying concentrations. Cohen and Pfaff1 used 1,666 units of penicillin per gram, with effectiveness, in impetigo contagiosa, carbuncles, herpes zoster with secondary impetigo and sycosis barbae. Johnson2 reported excellent results in the same type of cases using a concentration of 166 units per gram of ointment base. Vesicular and intertriginous fungous infections of the feet having secondary invasion by staphylococci and streptococci constitute a large group of conditions in patients References 1. Cohen, T. M., and Pfaff, R. O.: Penicillin in Dermatologic Therapy: Report of Results in One Hundred Cases , Arch. Dermat. & Syph. 51:172-177 ( (March) ) 1945. 2. Johnson, H. M.: Penicillin Ointment for Pyodermas, to be published.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: May 1, 1947

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