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ACCIDENTAL INOCULATION WITH SPIROCHAETA PALLIDA

ACCIDENTAL INOCULATION WITH SPIROCHAETA PALLIDA Abstract One of the hazards connected with clinical and experimental studies on syphilis is the possible accidental inoculation of the worker with Spirochaeta pallida.cian who treats syphilis or who handles syphilitic animals is liable to be inadvertently stuck, scratched, bitten or in other ways contaminated with spirochetes. The literature contaicon-atainsof such accidents with organisms obtained from both human and animal sources. However, there have been no publishedts of instances in which there was reasonable certainty that spirochetes from an experimental animal had entered the body but in which actual infection did not subsequently occur. In the case to be reported accidental injection of S. pallida probably did take place without the dissemination of the organisms and frank syphilis ensuing. In addition to this report, a summary of current opinion as to the procedure of choice in the event of such an accident is recorded. REPORT OF A CASE In February 1938 References 1. Metchnikoff, E., and Roux, E.: Etudes expérimentales sur la syphilis. Cinquième mémoire , Ann. Inst. Pasteur 20:785, 1906. 2. Buschke, A.: Ueber die Beziehung der experimentell erzeuten Tiersyphilis zur menschlichen Lues , Deutsche med. Wchnschr. 60:1783, 1913.Crossref 3. Graetz, F., and Delbanco, E.: Beiträge zum Studium der Histo-Pathologie der experimentellen Kaninchensyphilis , Med. Klin. 10:420, 1914. 4. Levaditi, C., and Marie, A.: Etude sur le tréponème pâle? Compt. rend. Soc. de biol. 91:911, 1924 5. Wakerlin, G.E.: Laboratory Infection in Man by the Spirocheta Pallida of Experimental Rabbit Syphilis , J. A. M. A. 98:479 ( (Feb. 6) ) 1932.Crossref 6. Personal communication to the author. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

ACCIDENTAL INOCULATION WITH SPIROCHAETA PALLIDA

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1941 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1941.01500050108010
Publisher site
See Article on Publisher Site

Abstract

Abstract One of the hazards connected with clinical and experimental studies on syphilis is the possible accidental inoculation of the worker with Spirochaeta pallida.cian who treats syphilis or who handles syphilitic animals is liable to be inadvertently stuck, scratched, bitten or in other ways contaminated with spirochetes. The literature contaicon-atainsof such accidents with organisms obtained from both human and animal sources. However, there have been no publishedts of instances in which there was reasonable certainty that spirochetes from an experimental animal had entered the body but in which actual infection did not subsequently occur. In the case to be reported accidental injection of S. pallida probably did take place without the dissemination of the organisms and frank syphilis ensuing. In addition to this report, a summary of current opinion as to the procedure of choice in the event of such an accident is recorded. REPORT OF A CASE In February 1938 References 1. Metchnikoff, E., and Roux, E.: Etudes expérimentales sur la syphilis. Cinquième mémoire , Ann. Inst. Pasteur 20:785, 1906. 2. Buschke, A.: Ueber die Beziehung der experimentell erzeuten Tiersyphilis zur menschlichen Lues , Deutsche med. Wchnschr. 60:1783, 1913.Crossref 3. Graetz, F., and Delbanco, E.: Beiträge zum Studium der Histo-Pathologie der experimentellen Kaninchensyphilis , Med. Klin. 10:420, 1914. 4. Levaditi, C., and Marie, A.: Etude sur le tréponème pâle? Compt. rend. Soc. de biol. 91:911, 1924 5. Wakerlin, G.E.: Laboratory Infection in Man by the Spirocheta Pallida of Experimental Rabbit Syphilis , J. A. M. A. 98:479 ( (Feb. 6) ) 1932.Crossref 6. Personal communication to the author.

Journal

Archives of Dermatology and Syphilology – American Medical Association

Published: Nov 1, 1941

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