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K. Landsteiner (1936)
Studies on Sensitization of Animals with Simple Chemical Compounds: Anaphylaxis Induced by ArsphenamineJ. Exper. Med., 64
K. Landsteiner (1915)
Untersuchung der Spezifizität von Serumreactionen durch Einführung verschiedenartiger Gruppen in EiweissZentralbl. f. Physiol., 30
R. Lauf (1935)
Untersuchungen über die Salvarsanüberempfindlichkeit des MeerschweinchensZtschr. f. Immunitätsforsch. u. exper. Therap., 86
K. Landsteiner, J. Jacobs (1936)
STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDSThe Journal of Experimental Medicine, 64
M. Walzer (1938)
A critical review of the recent literature on the dust atopen and on vitamin C in relation to hypersensitivenessJournal of Allergy, 10
F. Cormia (1937)
Experimental Arsphenamine Dermatitis: the Influence of Vitamin C in the Production of Arsphenamine Sensitiveness.Canadian Medical Association journal, 36 4
The arsphenamine was donated by the Abbott Laboratories
W. Jadassohn (1934)
Untersuchungen über den Mechanismus der anaphylaktisch-urtikariellen Reaktion (Schultz-Dalesche Versuche mit Haptenen)Arch. f. Dermat. u. Syph., 170
H. Haxthausen
Deliberationes Congressus dermatologorum internationalis IX-I, Budapestini, Sept. 13-21, 1935, Leipzig, Johann Ambrosius Barth, 1935, 1
K. Landsteiner, J. Scheer (1933)
ANAPHYLACTIC SHOCK BY AZODYESThe Journal of Experimental Medicine, 57
M. Sulzberger, B. Oser (1935)
Influence of Ascorbic Acid of Diet on Sensitization of Guinea Pigs to NeoarsphenamineProceedings of the Society for Experimental Biology and Medicine, 32
K. Landsteiner (1937)
Studies on Sensitization of Animals with Simple Chemical Compounds: Anaphylaxis Induced by Picrvl Chloride and 2:4 NitrochlorobenzeneJ. Exper. Med., 66
W. Frei (1928)
Ueber willkürliche Sensibilisierung gegen chemisch definierte Substanzen: II. Untersuchungen mit Neosalvarsan am TierKlin. Wchnschr., 7
F. Cormia (1937)
EXPERIMENTAL ARSPHENAMINE DERMATITIS: OBSERVATIONS ON ITS ALLERGIC NATURE, WITH SPECIAL ATTENTION TO THE SCHULTZ-DALE PHENOMENONArchives of Dermatology, 36
The mapharsen was donated by Parke
M. Walzer (1938)
Critical Review of Recent Literature on Dust and on Vitamin C in Relationship to HypersensitivenessJ. Allergy, 10
C. Bruck (1910)
Experimentelle Untersuchungen über das Wesen der ArzneiexanthemeBerl. klin. Wchnschr., 47
H. Fierz, W. Jadassohn, W. Stoll (1937)
ANAPHYLACTIC SENSITIZATION WITH CHEMICALLY DEFINITE COMPOUNDSThe Journal of Experimental Medicine, 65
W. Frei, M. Sulzberger (1938)
Further Studies in Arsphenamine Hypersensitiveness in Guinea Pigs: I. Cutaneous and Anaphylactic Responses to Old Arsphenamine and to Neoarsphenamine after Sensitization with Old Arsphenamine1Journal of Investigative Dermatology, 1
F. Cormia (1938)
Experimental Arsphenamine Sensitization: Further Observations on the Reactions to Arsphenamine in Guinea Pigs Given Staphylococcus Toxin, and in Guinea Pigs with Induced Streptococcal Infection1Journal of Investigative Dermatology, 1
F. Cormia (1936)
Experimental Arsphenamine Dermatitis.Canadian Medical Association journal, 34 3
P. Kallós (1935)
Experimentelle Untersuchungen über SalvarsanallergieKlin. Wchnschr., 14
H. Swift (1912)
ANAPHYLAXIS TO SALVARSANJAMA
A. Wolff-Eisner (1907)
Ueber die Urticaria vom Standpunkt der neuen Erfahrungen über Empfindlichkeit gegenüber körperfremden Eiweiss-substanzenDermat. Zentralbl., 10
M. Sulzberger, J. Goodman (1938)
Allergy in dermatology: A critical review of recent contributionsJournal of Allergy, 9
Abstract In 1907 Wolff-Eisner1 stated the belief that simple chemical compounds act as sensitizing agents by means of their conjugation with autochthonous body protein. Recent experimental work has refocused attention on the problem of hypersensitivity to simple chemicals, in its relation not only to the development of delayed cutaneous hypersensitivity of the cellular type but also to the induction of anaphylactic states. In the light of this work it seemed advisable to reexamine the data pertaining to sensitiveness to arsphenamine and to perform experiments to clarify further the fundamental concepts of the pathogenesis of cutaneous hypersensitivity to arsphenamine. The original experimental work on the production of cutaneous sensitivity to arsphenamine in the guinea pig was done by Frei.2 The various factors that contribute to the development of the sensitivity have recently been summarized.3 The attempted linkage of the sensitivity (as it exists in animals) with the induction, by References 1. Wolff-Eisner, A.: Ueber die Urticaria vom Standpunkt der neuen Erfahrungen über Empfindlichkeit gegenüber körperfremden Eiweiss-substanzen , Dermat. Zentralbl. 10:164, 1907. 2. Frei, W.: Ueber willkürliche Sensibilisierung gegen chemisch definierte Substanzen: II. Untersuchungen mit Neosalvarsan am Tier , Klin. Wchnschr. 7: 1026 ( (May 27) ) 1928.Crossref 3. Frei, W., and Sulzberger, M. B.: Further Studies in Arsphenamine Hypersensitiveness in Guinea Pigs: I. Cutaneous and Anaphylactic Responses to Old Arsphenamine and to Neoarsphenamine After Sensitization with Old Arsphenamine , J. Invest. Dermat. 1:191 ( (June) ) 1938.Crossref 4. Cormia, F. E.: Experimental Arsphenamine Sensitization: Further Observations on Reactions to Arsphenamine in Guinea Pigs Given Staphylococcus Toxin, and in Guinea Pigs with Induced Streptococcal Infection , J. Invest. Dermat. 1:199 ( (June) ) 1938.Crossref 5. Swift, H. F.: Anaphylaxis to Salvarsan , J. A. M. A. 59:1236 ( (Oct. 5) ) 1912.Crossref 6. Bruck, C.: Experimentelle Untersuchungen über das Wesen der Arzneiexantheme , Berl. klin. Wchnschr. 47:517, 1910. 7. Landsteiner, K., and Lampl, H.: Untersuchung der Spezifizität von Serumreactionen durch Einführung verschiedenartiger Gruppen in Eiweiss , Zentralbl. f. Physiol. 30:329 ( (July 15) ) 1915. 8. Landsteiner, K., and van der Scheer, J.: Anaphylactic Shock by Azodyes , J. Exper. Med. 57:633 ( (April) ) 1933.Crossref 9. Jadassohn, W., and Schaaf, F.: Untersuchungen über den Mechanismus der anaphylaktisch-urtikariellen Reaktion (Schultz-Dalesche Versuche mit Haptenen) , Arch. f. Dermat. u. Syph. 170:33 ( (April) ) 1934.Crossref 10. Fierz, H. E.; Jadassohn, W., and Stoll, W.: Anaphylactic Sensitization with Chemically Definite Compounds , J. Exper. Med. 65:339 ( (March) ) 1937.Crossref 11. Lauf, R.: Untersuchungen über die Salvarsanüberempfindlichkeit des Meerschweinchens , Ztschr. f. Immunitätsforsch. u. exper. Therap. 86:49 ( (Oct. 3) ) 1935. 12. Landsteiner, K., and Jacobs, J.: Studies on Sensitization of Animals with Simple Chemical Compounds: Anaphylaxis Induced by Arsphenamine , J. Exper. Med. 64:717 ( (Nov.) ) 1936.Crossref 13. Landsteiner, K., and Chase, M. W.: Studies on Sensitization of Animals with Simple Chemical Compounds: Anaphylaxis Induced by Picrvl Chloride and 2:4 Nitrochlorobenzene , J. Exper. Med. 66:337 ( (Sept.) ) 1937.Crossref 14. Sulzberger, M. B., and Goodman, J.: Allergy in Dermatology: Critical Review of Some Recent Contributions , J. Allergy 8:385 ( (May) ) 1937.Crossref 15. Haxthausen, H.: Foreign Protein as Auxiliary Factor in Cutaneous Allergy Toward Mercurial Salts and Other Non-Antigenic Substances , in Deliberationes Congressus dermatologorum internationalis IX-I, Budapestini, Sept. 13-21, 1935, Leipzig, Johann Ambrosius Barth, 1935 , vol. 1, p. 201. 16. Kallós, P., and Kallós-Deffner, L.: Experimentelle Untersuchungen über Salvarsanallergie , Klin. Wchnschr. 14:1074 ( (July 27) ) 1935.Crossref 17. Cormia, F. E.: Experimental Arsphenamine Dermatitis: Observations on Its Allergic Nature, with Special Attention to the Schultz-Dale Phenomenon , Arch. Dermat. & Syph. 36:970 ( (Nov.) ) 1937. 18. Cormia, F. E.: Experimental Arsphenamine Dermatitis , Canad. M. A. J. 34:272 ( (March) ) 1936. 19. The mapharsen was donated by Parke , Davis & Company, Montreal, Canada. 20. The arsphenamine was donated by the Abbott Laboratories , Montreal, Canada. 21. Cormia, F. E.: Unpublished data. 22. Sulzberger, M. B., and Oser, B. L.: Influence of Ascorbic Acid of Diet on Sensitization of Guinea Pigs to Neoarsphenamine , Proc. Soc. Exper. Biol. & Med. 32:716 ( (Feb.) ) 1935. 23. Cormia, F. E.: Experimental Arsphenamine Dermatitis: Influence of Vitamin C in the Production of Arsphenamine Sensitiveness , Canad. M. A. J. 36:392 ( (April) ) 1937. 24. Walzer, M.: Critical Review of Recent Literature on Dust and on Vitamin C in Relationship to Hypersensitiveness , J. Allergy 10:72 ( (Nov.) ) 1938.
Archives of Dermatology and Syphilology – American Medical Association
Published: Jan 1, 1941
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