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UNSATURATED FATTY ACIDS IN ECZEMA: OBSERVATIONS ON ACNE VULGARIS, PSORIASIS, XANTHOMA TUBEROSUM AND XANTHOMA PALPEBRARUM

UNSATURATED FATTY ACIDS IN ECZEMA: OBSERVATIONS ON ACNE VULGARIS, PSORIASIS, XANTHOMA TUBEROSUM... Abstract Hansen reported originally that the degree of unsaturation of fatty acids in the blood serum, as measured by the level of iodine absorption, was lower in infants with eczema than in normal controls.1 This work was followed by studies on the iodine absorption of the serum of rats on fat-free diets, and it was observed that the serum of normal rats was much more unsaturated (i. e., absorbed much more iodine) than that of the animals on the restricted diet.2 Later changes in the lipid content of the serum and the therapeutic effects of various oils were observed in patients with infantile eczema. Hansen concluded from this work that as the iodine number of the serum rose a parallel improvement of the cutaneous condition resulted, regardless of whether the greater unsaturation of the lipids was effected by feeding oil or by applying coal tar locally.3 Faber References 1. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 30:1198, 1933. 2. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 30:1200, 1933. 3. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 31:160, 1933. 4. Faber, H. K., and Roberts, D. B.: J. Pediat. 6:490, 1935. 5. Cornbleet, T.: Use of Maize Oil (Unsaturated Fatty Acids) in the Treatment of Eczema , Arch. Dermat. & Syph. 31:224 ( (Feb.) ) 1935 6. Taub, S. J., and Zakon, S. J.: The Use of Unsaturated Fatty Acids in the Treatment of Eczema , J. A. M. A. 105:1675 ( (Nov. 23) ) 1935. 7. Bloor, W. R.: J. Biol. Chem. 77:53, 1928 8. 82:273, 1929. 9. Yasuda, M.: J. Biol. Chem. 94:401, 1931. 10. Some of the clinical observations reported here were made on patients who attended the dermatologic clinic of the University of California. 11. Wilson, W. R., and Hanner, J. P.: J. Biol. Chem. 106:323, 1934. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

UNSATURATED FATTY ACIDS IN ECZEMA: OBSERVATIONS ON ACNE VULGARIS, PSORIASIS, XANTHOMA TUBEROSUM AND XANTHOMA PALPEBRARUM

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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1937 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1937.01470210053005
Publisher site
See Article on Publisher Site

Abstract

Abstract Hansen reported originally that the degree of unsaturation of fatty acids in the blood serum, as measured by the level of iodine absorption, was lower in infants with eczema than in normal controls.1 This work was followed by studies on the iodine absorption of the serum of rats on fat-free diets, and it was observed that the serum of normal rats was much more unsaturated (i. e., absorbed much more iodine) than that of the animals on the restricted diet.2 Later changes in the lipid content of the serum and the therapeutic effects of various oils were observed in patients with infantile eczema. Hansen concluded from this work that as the iodine number of the serum rose a parallel improvement of the cutaneous condition resulted, regardless of whether the greater unsaturation of the lipids was effected by feeding oil or by applying coal tar locally.3 Faber References 1. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 30:1198, 1933. 2. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 30:1200, 1933. 3. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 31:160, 1933. 4. Faber, H. K., and Roberts, D. B.: J. Pediat. 6:490, 1935. 5. Cornbleet, T.: Use of Maize Oil (Unsaturated Fatty Acids) in the Treatment of Eczema , Arch. Dermat. & Syph. 31:224 ( (Feb.) ) 1935 6. Taub, S. J., and Zakon, S. J.: The Use of Unsaturated Fatty Acids in the Treatment of Eczema , J. A. M. A. 105:1675 ( (Nov. 23) ) 1935. 7. Bloor, W. R.: J. Biol. Chem. 77:53, 1928 8. 82:273, 1929. 9. Yasuda, M.: J. Biol. Chem. 94:401, 1931. 10. Some of the clinical observations reported here were made on patients who attended the dermatologic clinic of the University of California. 11. Wilson, W. R., and Hanner, J. P.: J. Biol. Chem. 106:323, 1934.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Mar 1, 1937

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