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S. Taub, S. Zakon (1935)
THE USE OF UNSATURATED FATTY ACIDS IN THE TREATMENT OF ECZEMA: (ATOPIC DERMATITIS, NEURODERMATITISJAMA, 105
Morio. Yasuda (1931)
THE DETERMINATION OF THE IODINE NUMBER OF LIPIDSJournal of Biological Chemistry, 94
W. Wilson, J. Hanner (1934)
CHANGES OF TOTAL LIPID AND IODINE NUMBER OF BLOOD FAT IN ALIMENTARY LIPEMIAJournal of Biological Chemistry, 106
T. Cornbleet, E. Pace (1935)
USE OF MAIZE OIL (UNSATURATED FATTY ACIDS) IN THE TREATMENT OF ECZEMA: PRELIMINARY REPORTArchives of Dermatology, 31
W. Bloor (1928)
THE DETERMINATION OF SMALL AMOUNTS OF LIPID IN BLOOD PLASMAJournal of Biological Chemistry, 77
Abstract Hansen reported originally that the degree of unsaturation of fatty acids in the blood serum, as measured by the level of iodine absorption, was lower in infants with eczema than in normal controls.1 This work was followed by studies on the iodine absorption of the serum of rats on fat-free diets, and it was observed that the serum of normal rats was much more unsaturated (i. e., absorbed much more iodine) than that of the animals on the restricted diet.2 Later changes in the lipid content of the serum and the therapeutic effects of various oils were observed in patients with infantile eczema. Hansen concluded from this work that as the iodine number of the serum rose a parallel improvement of the cutaneous condition resulted, regardless of whether the greater unsaturation of the lipids was effected by feeding oil or by applying coal tar locally.3 Faber References 1. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 30:1198, 1933. 2. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 30:1200, 1933. 3. Hansen, A. E.: Proc. Soc. Exper. Biol. & Med. 31:160, 1933. 4. Faber, H. K., and Roberts, D. B.: J. Pediat. 6:490, 1935. 5. Cornbleet, T.: Use of Maize Oil (Unsaturated Fatty Acids) in the Treatment of Eczema , Arch. Dermat. & Syph. 31:224 ( (Feb.) ) 1935 6. Taub, S. J., and Zakon, S. J.: The Use of Unsaturated Fatty Acids in the Treatment of Eczema , J. A. M. A. 105:1675 ( (Nov. 23) ) 1935. 7. Bloor, W. R.: J. Biol. Chem. 77:53, 1928 8. 82:273, 1929. 9. Yasuda, M.: J. Biol. Chem. 94:401, 1931. 10. Some of the clinical observations reported here were made on patients who attended the dermatologic clinic of the University of California. 11. Wilson, W. R., and Hanner, J. P.: J. Biol. Chem. 106:323, 1934.
Archives of Dermatology and Syphilology – American Medical Association
Published: Mar 1, 1937
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