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Clinical Assessment of Patients With Recalcitrant Psoriasis in a Randomized, Observer-Blind, Vehicle-Controlled Trial Using Indigo Naturalis

Clinical Assessment of Patients With Recalcitrant Psoriasis in a Randomized, Observer-Blind,... STUDY Clinical Assessment of Patients With Recalcitrant Psoriasis in a Randomized, Observer-Blind, Vehicle-Controlled Trial Using Indigo Naturalis Yin-Ku Lin, MD; Chee-Jen Chang, PhD; Ya-Ching Chang, MD; Wen-Rou Wong, MD; Shu-Chen Chang, PhD; Jong-Hwei Su Pang, PhD Objective: To evaluate the efficacy and safety of treat- thema, scaling, and induration scores and the clearing ment with indigo naturalis in patients with recalcitrant percentage of the target plaque lesion assessed by 2 blinded plaque-type psoriasis. observers. Design: Randomized, observer-blind, vehicle-con- Results: Significant reductions in the sum of scaling, ery- trolled, intrapatient comparison study. thema, and induration scores (P.001) (mean score, 6.3 after indigo naturalis treatment vs 12.8 in control sub- Setting: Ambulatory department of a hospital. jects) and plaque area percentage (P.001) (mean per- centage, 38.5% after indigo naturalis treatment vs 90% Participants: Forty-two outpatients with chronic plaque in controls) were achieved with topical application of in- psoriasis were enrolled in the study from May 1, 2004, digo naturalis ointment. Approximately 31 of 42 pa- to April 30, 2005. tients (74%) experienced clearance or near clearance of their psoriasis in the indigo ointment–treated lesion. Intervention: The patients applied either indigo natu- ralis ointment or vehicle ointment topically to each of 2 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

Clinical Assessment of Patients With Recalcitrant Psoriasis in a Randomized, Observer-Blind, Vehicle-Controlled Trial Using Indigo Naturalis

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References (12)

Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/archderm.144.11.1457
pmid
19015420
Publisher site
See Article on Publisher Site

Abstract

STUDY Clinical Assessment of Patients With Recalcitrant Psoriasis in a Randomized, Observer-Blind, Vehicle-Controlled Trial Using Indigo Naturalis Yin-Ku Lin, MD; Chee-Jen Chang, PhD; Ya-Ching Chang, MD; Wen-Rou Wong, MD; Shu-Chen Chang, PhD; Jong-Hwei Su Pang, PhD Objective: To evaluate the efficacy and safety of treat- thema, scaling, and induration scores and the clearing ment with indigo naturalis in patients with recalcitrant percentage of the target plaque lesion assessed by 2 blinded plaque-type psoriasis. observers. Design: Randomized, observer-blind, vehicle-con- Results: Significant reductions in the sum of scaling, ery- trolled, intrapatient comparison study. thema, and induration scores (P.001) (mean score, 6.3 after indigo naturalis treatment vs 12.8 in control sub- Setting: Ambulatory department of a hospital. jects) and plaque area percentage (P.001) (mean per- centage, 38.5% after indigo naturalis treatment vs 90% Participants: Forty-two outpatients with chronic plaque in controls) were achieved with topical application of in- psoriasis were enrolled in the study from May 1, 2004, digo naturalis ointment. Approximately 31 of 42 pa- to April 30, 2005. tients (74%) experienced clearance or near clearance of their psoriasis in the indigo ointment–treated lesion. Intervention: The patients applied either indigo natu- ralis ointment or vehicle ointment topically to each of 2

Journal

JAMA Dermatology – American Medical Association

Published: Nov 1, 2008

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