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Purpose: We compared subjective quality of life, well-being, urinary tract symptoms, and distress in patients after radical cystectomy and orthotopic urinary reconstruction with those in a matched control population.
Clinically insignificant prostate cancer, defined as at most microscopic foci of Gleason grade ≤3 disease in the radical prostatectomy specimen, has been recognized in some low risk (PSA <10, biopsy Gleason score ≤6, clinical T1c, 2a) patients with minimal biopsy cancer volume. The purpose of...
Nitric oxide (NO) is an important signaling molecule for ischemia, inflammation, angiogenesis, immune response, and cell growth and differentiation. It has recently been shown that increased production of NO within various human cancers may contribute to tumor angiogenesis, tumor growth and...
Purpose: We introduce the operative technique of laparoscopic radical cystectomy and orthotopic ileal neobladder with a Studer limb performed completely intracorporeally.
Purpose: Health-related quality of life after urinary diversion has been increasingly recognized as an important outcome measure. However, few studies have directly compared patients with an ileal conduit with those with a continent orthotopic neobladder, and even fewer have used validated...
Objective: To compare the health-related quality of life (HRQoL) after radical cystectomy in patients with an ileal conduit or an orthotopic neobladder.
Pathologic evaluation of the prostate biopsy provides the clinician with a wealth of information. Identifying needle biopsy parameters predictive of pathological stage and tumor volume at radical prostatectomy has become a major focus in the field of prostate pathology. From a review of the...
Objectives For many men with localized prostate cancer, there is no definite answer or unequivocal choice regarding treatment modality. This high-stakes treatment decision is made in the context of great uncertainty. The purpose of this study is to systematically document meaningful and relevant...
Purpose The risk of developing any cancer in carriers of the I1307K mutation of the adenopolyposis coli (APC) gene is significantly increased (odds ratio 1.5, P = 0.01). One of the cancers associated with the I1307K mutation is prostate cancer (odds ratio 2.0, P = 0.14). Also, there is an...
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