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In addition to the postjunctional neurotoxins that bind to acetylcholine receptors, cobra venoms contain large quantities of similar polypeptides that act directly on cell membranes. These toxins (“cardiotoxins”, “cytotoxins”, “direct lytic factors”, “membrane toxins”) act in vivo...
In developing countries there is increasing interest and research in the area of herbal medicines as an approach to reducing costs of health care. The chemically complex nature of these medicinal preparations results in a significant increased risk of toxicity, including genotoxicity. A total of...
Toxic-shock syndrome (TSS) toxin-1 (TSST-1), an exotoxiri produced by Staphylococcus aureus , has been implicated in the development of TSS. The toxin's unique pathobiological properties, including pyrogenicity, ability to enhance susceptibility to lethal endotoxin shock, and alteration of T...
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