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There is a significant clinical need to develop alternatives to autografts and allografts for bone grafting procedures. Porous, biodegradable scaffolds based on the biopolymer chitosan have been investigated as bone graft substitutes, and the addition of calcium phosphate to these scaffolds has...
Neovascularization can be improved by means of polymer scaffolds supporting endothelial progenitor cells. The aim of the present study was to investigate whether human early endothelial progenitor cells (eEPCs) could be efficiently cultured in a hyaluronan-based non-woven mesh (HYAFFÂ®-11)....
Long term viability of thick three dimensional (3D) engineered tissue constructs is a major challenge. Addressing it requires development of vessel like network, which will allow the survival of the construct in vitro and its integration in vivo owing to improved vascularization after...
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