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Motor cortical organization has commonly been conceived as somatotopically ordered, with single body parts controlled from individual patches of cortical tissue. An opposing viewpoint suggests that motor cortex has a distnbuted, adaptive, and dynamic organi zation that underlies movement...
Antibodies reacting with carbohydrate epitopes on neural glycoconjugates are present in several forms of neuropathy. These include monoclonal antibodies to the myelin-associated glycoprotein (MAG) and to gan gliosides in patients with neuropathy in association with IgM gammopathy, as well as...
Neurotransmitters are normally released from neurons via calcium-dependent exocytosis of synaptic vesicles. However, after blockade of vesicular release by removal of calcium, or treatment with tetanus toxin, neurotransmitter release can still occur. In the case of GABA, nonvesicular release...
Under normal conditions in the central nervous system (CNS), the calcium ion (Ca 2+ ) is known to mediate a variety of neuronal functions, including synaptic neurotransmitter release, neuronal plasticity, protein phos phorylation, and gene expression. Whereas intracellular calcium concentrations...
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