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ATP-sensitive potassium channels open when cytoplasmic levels of ATP drop, thus linking membrane potential to the metabolic state of the cell. Cloning studies have suggested that these channels are related structurally to the inward rectifier family of potassium channels, with two putative...
The etiology of multiple sclerosis (MS) has not yet been defined. Based on analysis of prevalence, incidence, and migration studies, it is likely that one or more environmental factors, probably infectious in origin, initiates the disease. Canine distemper virus appears to be an attractive...
Migraine headache is the first neurological condition treatable by a drug targeted to a specific receptor binding site. Originally viewed as a disorder of brain blood vessels, migraine may have as its biological basis a disturbance in brain function. Regarding therapy, recent molecular data...
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