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Acquisition by pneumococcal variants of M protein and of capsular polysaccharide different from those present in the parent strain has been effected in vitro by means of transforming reactions with extracts of heterologous encapsulated pneumococci. Similar transformations have been accomplished...
Acute disseminated encephalomyelitis has been produced in rhesus monkeys by injection of their own brain tissue, removed surgically and incorporated with adjuvants. Footnotes Submitted: 30 November 1948
Treponema pallida were extracted from rabbit testicular syphilomas and suspended in a special medium in which the organisms remain motile and infectious for several days. On incubation of such suspensions with syphilitic rabbit or human sera and guinea pig complement, the treponemes became...
The isolation and characterization of a type-specific M protein from pneumococcus are described. This protein is similar chemically in all respects studied to the M proteins of group A streptococci. No immunological crossreactions have been observed, however, between M proteins of the two...
It has proved possible to transform an extreme rough variant of pneumococcus back to the rough state by the action of the desoxyribonucleate fractions of either rough or Type III smooth pneumococci. In a second step, the rough pneumococci produced by this transformation were further changed to...
The method of replicas has been applied to the study with the electron microscope of blood cells and bacteria. The results indicate that the method can reveal details of intracellular structures. Nuclei can be perceived, and also cytoplasmic bodies such as mitochondria and vacuoles. Footnotes...
A method for preparing replicas of salivary gland chromosomes for electron microscopy is described. Electron micrographs of these replicas show that the giant chromosomes are composed of a series of small granules of approximately equal size arranged transversely across the chromosome. In...
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