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There is emerging evidence to support a link between inflammation and atrial fibrillation (AF). Lipopolysaccharide (LPS) infusion is a well established experimental model used to investigate host systemic inflammatory responses. It was hypothesized that LPS challenge, by virtue of its provoked...
Age-adjusted sudden cardiac death rates are highest for black patients compared with other racial groups. The prophylactic implantation of an implantable cardioverter-defibrillator (ICD) provides a significant reduction in sudden cardiac death and overall mortality in patients after myocardial...
A previous study of electrocardiography at rest showed that anti-Ro/SSA–positive patients with connective tissue disease (CTD) frequently had corrected QT (QTc) interval prolongation. Because QTc interval prolongation is a definite risk factor for arrhythmic sudden death in the general...
Endothelial dysfunction is considered one of the mechanisms underlying vasospastic angina pectoris (VSA). It is also known that smokers have abnormalities in endothelial dysfunction. Although smoking is a major risk factor for coronary artery disease, microvascular abnormalities have not been...
This study was conducted to investigate the effect of growth hormone (GH) replacement on cardiac function assessed by standard or tissue Doppler echocardiography in GH deficiency. Ten patients (mean age 47 ± 14 years) received GH at a dose of 1.0 IU/day (6 times/week). After 6 months of GH...
Interatrial block (IAB; P-wave duration ≥110 ms) is highly prevalent and is strongly associated with atrial tachyarrhythmias and left atrial dysfunction. Very few studies have examined IAB in young healthy subjects. The aim of the present study was to demonstrate the prevalence of IAB and its...
The use of, factors associated with, and long-term outcomes related to statin therapy in patients with acute coronary syndromes and low-density lipoprotein (LDL) levels <100 mg/dl at the time of hospital presentation are unclear. This report describes the use of statins at hospital discharge in...
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