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The secretion of insulin-like growth factor-I and sex hormones declines with age. These changes are paralleled with the age-related decrease in muscle mass and muscle function. The aim of this study was to determine whether serum insulin-like growth factor-I (IGF-I) and sex hormone (binding...
Elderly subjects have a lower energy requirement compared to young adults as a result of lower physical activity and a lower basal metabolic rate. A lower energy intake in the elderly could lead to undesirable low intakes of essential nutrients. The reduction of the energy turnover is caused by,...
Type 2 diabetes mellitus is a common chronic disease of older men, affecting an estimated 40% of American men over age 60 1 . This paper reviews epidemiological aspects of diabetes mellitus in the aging male, with emphasis on the impact of diabetes in older American men. The first part of the...
The aim of the study was to evaluate the independent ‘net’ effects of hormonal variables (estradiol, free testosterone and dehydroepiandrosterone sulfate (DHEAS) levels) and lifestyle variables (alcohol consumption, coffee drinking, cigarette smoking, physical activity and muscle strength) on...
The body's handling of drugs can be significantly altered with age. An overview of the way the body manages the movement of drugs through the body, pharmacokinetics, and their interaction with the body to cause their effects, pharmacodynamics, is provided. Clinically significant changes rather...
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