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Objective . This study examined the effects of daily and cumulative oral corticosteroid doses on the risk of fractures. Methods . Information was obtained from the General Practice Research Database, which contains medical records of general practitioners in England and Wales. The study included...
Objective . To establish the prevalence of work disability and predictors of change in employment status in patients with early rheumatoid arthritis (RA). Setting . The Norfolk Arthritis Register (NOAR), a primary‐care based inception cohort of patients with recent‐onset inflammatory...
Objectives . To investigate regional cerebral blood flow by 99m Tc‐hexamethylpropylenamineoxime (HMPAO) single photon emission computed tomography (SPECT) in a series of 40 patients (mean age 58.5±11.5 yr) affected by systemic sclerosis (SSc) in comparison with age‐matched healthy controls....
Objective . To study the specificity of the peripheral blood mononuclear cell (PBMC) response to peptides derived from human cartilage glycoprotein‐39 (HC gp‐39) in patients with rheumatoid arthritis (RA) and the correlation between this response and disease activity. Methods . RA patients,...
Objectives . Both increased and decreased apoptosis may be involved in generating autoimmunity. This study addressed the question of whether apoptosis and apoptosis‐regulating proteins are altered in systemic sclerosis (SSc). Patients and methods . Peripheral lymphocytes of 39 SSc patients and...
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