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Omes of somes and cytes and phages Can you rhyme these lines? Bone marrow dendrocytes are turned on by bacterial LPS; macrophages are from mice; endosomes grow from internalized red latex (styrene) beads; latex beads are bait for catching phagosomes. No rhymes? Me neither. But the prose from...
Many biologically active agents exert a pleiotropic response in cells and tissues. This presents challenges in descriptive and comparative analysis of the proteome in response to these agents. Although free‐flow electrophoresis has been applied in a number of proteomic studies as a protein...
Clinical proteomics faces extremely complex and variable data. Here, we present an updated version of the Griss Proteomics Database Engine (GPDE): A free biological proteomic database specifically designed for clinical proteomics and biomarker discovery (). It combines experiments based on...
The oleic acid‐functionalized magnetite nanoparticles (OA‐Fe3O4) with mean diameter of about 15 nm were synthesized through a low‐cost, one‐pot method and were designed as hydrophobic probes to realize the convenient, efficient and fast concentration of low‐concentration peptides...
SOX2 is a key gene implicated in maintaining the stemness of embryonic and adult stem cells that appears to re‐activate in several human cancers including glioblastoma multiforme. Using immunoprecipitation (IP)/MS/MS, we identified 144 proteins that are putative SOX2 interacting proteins. Of...
The ability to investigate the proteome of formalin‐fixed, paraffin‐embedded (FFPE) tissues can be considered a major recent achievement in the field of clinical proteomics. However, gel‐based approaches to the investigation of FFPE tissue proteomes have lagged behind, mainly because of...
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