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Almost all the epidemiological studies that aimed to answer the question of the relationship between heart rate and all-cause or cardiovascular morbidity and mortality reported that a high heart rate was associated with a higher risk of all-cause mortality and cardiovascular events. This...
Although essential hypertension seems to have a strong hereditary component, the triggering mechanism is unclear. It is likely that the central nervous system via autonomic sympathetic overactivation plays a key role in the development of hypertension. High heart rate has proven to be a strong...
Alterations in glucose and lipid metabolism frequently cluster with overweight, obesity as well as hypertension in the clinical condition known as metabolic syndrome . The “cardiometabolic clustering” is characterized by well-known alterations that increase cardiovascular risk profile such as...
Heart rate is a major determinant of myocardial oxygen consumption and of cardiac work, and thus reduction of heart rate may represent an important strategy for the treatment of patients with a wide range of cardiac disorders. In addition, several experimental lines of research point to high...
A number of epidemiologic studies and several experimental lines of research point to high heart rate as a main risk factor for cardiovascular disease. However, translating research into clinical practice has been a challenge throughout medical history. From the present symposium, it appears...
In both physiologic and pathological conditions, instantaneous heart rate value is the result of a rather complex interplay. It constantly varies under the influence of a number of factors: nonmodifiable and modifiable ones. Pharmacologic blockade with β -adrenergic antagonists and/or with...
Tachycardia is a strong predictor of both hypertension and excessive cardiovascular risk. This association is robust and prevails after multivariate adjustments for other cardiovascular risk factors. Despite the strong evidence, various guidelines do not list tachycardia as a risk factor because...
In the past 2 decades, there have been growing evidences that resting heart rate might be a marker of risk or even a risk factor for cardiovascular morbidity and mortality. This article reviews current evidences concerning the relation between heart rate and patients' outcome in different...
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