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Cardiovascular disease is the leading cause of morbidity and mortality with annual costs of care exceeding $300 billion dollars. Although screening tools are advocated for many cancers, the use of subclinical disease tests for cardiovascular disease are considered controversial. Health care...
Imaging for atherosclerotic disease as a modality of risk assessment to guide clinical intervention for primary prevention is becoming more widely acceptable. The greatest infomation about risk can be obtained by combining measures of atherosclerotic plaque burden with risk factors. Both contain...
X-ray computed tomography (CT) is widely available in the world and has the ability to provide high-definition, thin-section imaging of any body part. In particular, CT over the past decade has been shown in numerous publications to allow for quantitation of coronary calcification, a proven...
Over the last decade, there has been increased recognition that atherosclerosis imaging adds greatly to the ability to identify patients at high risk for cardiac events. Technologies such as electron beam computed tomography and carotid intimal media thickness have contributed significantly to...
In the context of the beneficial effects of statins, irrespective of the low-density lipoprotein cholesterol level (LDL-C) in the Heart Protection Study and the relatively poor event reduction (24%–37%) in the LDL-C reduction trials, electron beam tomography plaque imaging has provided the...
Fast, cross-sectional computed tomography (CT) imaging permits visualization of the coronary artery lumen after intravenous injection of contrast agent. Electron beam CT and multidetector row spiral CT have both been shown to allow detection of coronary artery stenoses with high sensitivity and...
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