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Submerged cultivation of a high yielding strain of Aspergillus terreus DRCC 122 for the production of lovastatin in the batch process had limited success with a maximum titre of 1270 mg l −1 in 288 h and an overall volumetric productivity of 4.41 mg l −1 h −1 in a 1000 l bioreactor. A cost...
The polyunsaturated fatty acid γ-linolenic acid (GLA,18:3ω6), which has several pharmaceutical properties, has been purified from the seed oil of three plant species, Anchusa azurea , Scrophularia sciophila and Echium fastuosum . The process consists of four main steps, (i) simultaneous...
A novel hybrid biological reactor which contained both suspended- and attached-growth biomass was developed by introducing porous materials into a regular activated sludge unit and used for the treatment of domestic wastewater. The development of suspended- and attached-growth biomass in this...
The production of cellulase-free thermostable xylanase was investigated with a locally isolated and identified strain, Clostridium absonum CFR-702 in a defined medium under anaerobic cultivation conditions at higher temperatures (above 65°C). Different fermentation conditions were standardised...
A study of the kinetics of the anaerobic digestion process of wastewater derived from the production of protein isolates from extracted sunflower flour was carried out in a laboratory-scale fluidised bed reactor with saponite as support for the mediating bacteria at mesophilic temperature...
Isoamyl isovalerate, an ester with apple flavour was synthesized using Rhizomucor miehei lipase immobilized on a weak anion-exchange resin (Lipozyme IM-20) by the direct esterification of isoamyl alcohol and isovaleric acid. Various reaction parameters including substrate concentration, enzyme...
The effect of oxygen on lipase production by Rhizopus arrhizus was studied under two operating modes, controlled dissolved oxygen concentration (DO) and controlled aeration rate. Lipase production depended more extensively on oxygen than cell growth. The intrinsic factor determining cell growth...
The extraction of an extracellular acid phosphatase from fermentation broth was carried out, using a reversed micellar system in an organic solvent. Process parameters were optimized for maximum extraction using 200 mM bis(2-ethylhexyl)sodium sulphosuccinate (AOT) in isooctane at 25°C. The...
Comparative studies were performed to develop a fermentation process for the production of rifamycin-B using Amycolatopsis mediterranei VA18. Wheat bran as substrate in solid state fermentation (SSF), and peanut meal and soybean with glucose were used as substrate for submerged fermentation...
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