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Summary Exposure of cultured neonatal rat heart cells to simulated ischaemia results in a cessation of the spontaneous contractile activity and changes at both the level of sarcolemmal phospholipid topology and the ultrastructural level. Reperfusion at a timepoint before irreversible cell damage...
Clever molecules Ion Channels: A Practical Approach. Edited by R. H. Ashley, 1995, Practical Approach Series No. 160, IRL Press at Oxford University Press, Oxford. 302 pp. £27.50 (pbk). ISBN 0 19 963474 2 (pbk). Advances in photosynthesis Molecular Processes of Photosynthesis , Volume 10 in:...
Summary The effect of a series of long-chain acyl-CoAs and acylcarnitines has been tested by differential scanning calorimetry on the gel-fluid transition of saturated phosphatidylcholines and of dielai-doylphosphatidylethanolamine (DEPE), and on the lamellar-hexagonal transition of DEPE. Both...
Summary Intracellular pH in bacteria can be measured efficiently between internal pH values of 6·D5 and 8·D5 with the fluorescent pH indicator 2′,7′-bis-(2-carboxyethyl)-5(and-6)-carboxyfluorescein (BCECF). A new fluorescent pH probe with a lower p K a (app) than BCECF was synthesized from...
Summary It is worthwhile emphasizing the importance of electron transport across lipid membranes. Mitochondrial and electron transport in chloroplasts were elucidated in great detail many years ago. Plasma membrane-bound electron transfer may be involved in several processes such as membrane...
Summary Functional K v 1.4 channels were stably expressed in filter-grown MDCK cells which form a polarized epithelium with two distinct plasma membrane domains: a basolateral and an apical cell surface. The Shaker-related K v 1.4 channels mediated in MDCK cells fast transient (A-type)...
Summary Twenty-one sequenced protein members of the epithelial Na + channel (ENaC) family have been identified and characterized in terms of their sizes, hydropathy profiles, sequence similarities and phylogenies. These proteins derive from mammals, the frog Xenopus laevis and the worm...
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