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The objective of the study was to determine the preferred treatment strategy for elderly patients with chronic nonvalvular atrial fibrillation (CNVAF). A Markov decision-analytic model was used to compare three treatment strategies for CNVAF: 1) warfarin; 2) aspirin; and 3) no treatment....
It has been suggested that clinical prediction rules are not reproducible, and that the most important variables frequently do not appear in replicate models. The authors studied the reproducibility of a validated rule for predicting radiographic evidence of pneumonia (ROC areas for the training...
A method is presented for helping patients who have laryngeal cancer to decide between laryngectomy and radiotherapy in cases where these treatments are deemed medically equivalent. The method is based on the model of additive conjoint measurement. The treat ment with the higher utility is...
Apparent low usage of formal decision techniques by general clinicians has raised questions about dissemination methods and about the techniques' perceived usefulness. Two literature searches examined whether use of formal decision techniques among clinicians had indeed failed to increase from...
A method for combining and comparing medical tests across studies or strata is presented. The area under the receiver operating characteristic (ROC) curve is the parameter of interest to be used for comparison. The combined area is a weighted average of the areas under the curve in each study or...
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