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In this work, we aimed to investigate the frequency, possible categories and clinical significance of circulating CD4 + ICOS + FoxP3 + T cells in patients with systemic lupus erythematosus (SLE). The frequency of circulating CD4 + ICOS + FoxP3 + T cells was analysed by flow-cytometric analysis in...
Systemic lupus erythematosus (SLE) is characterized by abnormalities in the function of T and B lymphocytes and in the signaling pathways induced through their receptors. Cbl-b is an intracellular adaptor protein that plays a key role in the negative regulation of lymphocyte activity. We explored...
Ischaemic colitis is relatively uncommon in systemic lupus erythematosus (SLE), with only very few case reports or case series in world literature. Ischaemic colitis occurs when SLE activity is high and is inarguably due to small vessel vasculitis affecting the large or small intestine. Ischaemic...